Protein Alignment Ctl1 and slc44a3

DIOPT Version :10

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_017949102.1
• Gene: slc44a3 / 100488884
• XenbaseID: XB-GENE-6050291
• Length: 652
• Species: Xenopus tropicalis
• Alignment Length: 656
• Identity: 194/656 - (29%)
• Similarity: 317/656 - (48%)
• Gaps: 76/656 - (11%)

  Fly     3 CAESKDGEGEAQNN-RPK-YRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDSFGNT 65
            |.|.:..|...|.. ||. ||.|||..||.::.:||..|:.||.::.|.|...|::.||||:||.
 Frog     4 CGEYQVSEVSRQRQWRPLIYRKCTDIPWLVLFFVFWSGLVFIAGYALVAGAAERLVFGYDSYGNV 68

  Fly    66 CGVKYNEKFQGFPLSGMNTLDKPELFYFD-----VKELK-KSLKICVKSCPAKTMTKGSELLEYY 124
            || :.|......|.||.:...:..:|:.|     ::.|| .|:.:||..||.:.:....|:..:.
 Frog    69 CG-RRNSPIPNAPFSGQDMTYRKHVFFLDSCNLEIRNLKINSVALCVSDCPQEQLNTLHEVQFFA 132

  Fly   125 SQTGTQLCKYDYNMQQLTTAGNDAKTFNFLGPCPSFPV--HESSPVLHRCVPKGTGEKVQN---- 183
            ...|:.||.|..|..:.||   ..|...:   ||..||  .:|.|:.:||||       ||
 Frog   133 KNNGSYLCVYKLNYTEYTT---HTKALEW---CPVLPVPSSKSFPLFNRCVP-------QNPDCY 184

  Fly   184 ------YYDMLNNWDVAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVI 242
                  ..:::|..|...:.:..|.:....:..:..||:.:|:.:|....::|.::..|...|:|
 Frog   185 SRFASVLINVVNEVDFFHRILSGIMAGKDNVIGLSILAVGLSVIMVLTFLFISTLLVHIFLTLLI 249

  Fly   243 VASVALTVALWYAYYNIRNKSGVNTQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKL 307
            ...:.::..||:.||:     .||.....||....|.:.:|..|::||:..|:|:..|:.|:..:
 Frog   250 FGLLFVSGVLWWLYYD-----HVNDPSYELETEKENAKFLLGFAIIATLVTIVLLTFIFVLRKSI 309

  Fly   308 AGLSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAH 372
            .....||....:.:..:|.|::.|:..|::||.:...||||::.|.|:
 Frog   310 QMTIQLFLVTSKFIRCMPLLVLQPVWTFVILIFYWVLWVAVLLSLGTS----------------- 357

  Fly   373 QQPLPANALFVSNSTDVNDLRPNARVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVA 437
                 .||          .:.|..:|||.....:|.|:|.:::|.|||.||..||||..::.|..
 Frog   358 -----GNA----------QVSPEGQVEYKPLAGIRYMWWYHLIGFIWTSEFFLACQQMIISGATV 407

  Fly   438 FWYFQKPTST---PTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECA 499
            .||..:..:.   |...::..:..|||||...|||:||:.:|||::|.|.:..|:...|  :.|:
 Frog   408 SWYLHRDKNKIRHPILSSLSLVFWYHLGTAIIGSFLITLMRIPRMVLCYTFQLLRDKPD--NVCS 470

  Fly   500 ACCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFIL 564
            .|.||||.|..:..|||::.|:.||||...|....||.:|..|:..:|.|...|:::|..|.|::
 Frog   471 RCTLKCCACSSFCFEKFLKSLDQNAYTASIINGTPFCTSANDAYGILAKNPPHVSSLNCSGVFLI 535

  Fly   565 FLGKVVVAALSGLIGIVLLKDKPGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDK 629
            .||||.|...:...|::.......|:.:..|::::..|::.::|..|||||.|:.:||||...|.
 Frog   536 LLGKVFVVCFTVFGGLMAFNYHRELHVWAIPLLLVAFFAYLVSHCFLSLFETVIHSLFLCYAVDI 600

  Fly   630 TLNGRS 635
            ..|..|
 Frog   601 ETNDGS 606

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	106/344 (31%)
slc44a3	XP_017949102.1	Choline_transpo	289..601	CDD:461337	107/345 (31%)