Protein Alignment Ctl1 and slc44a1

DIOPT Version :9

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_002934036.2
• Gene: slc44a1 / 100380051
• XenbaseID: XB-GENE-984336
• Length: 651
• Species: Xenopus tropicalis
• Alignment Length: 716
• Identity: 240/716 - (33%)
• Similarity: 380/716 - (53%)
• Gaps: 96/716 - (13%)

  Fly     1 MGCAESKDGEGEAQNNRPKYR-----SCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYD 60
            |||.      |..|:::..:|     ||||..||.::|:|.:.:..|..||...|...|:::|||
 Frog     1 MGCC------GSTQSSKRDWRPLEEHSCTDIPWLLLFILFCVGMGFICGFSIATGAASRLVSGYD 59

  Fly    61 SFGNTCGVKYNEKFQGFPLSGMNTLDKPELFYFD------VKELKKSLKICVKSCPAKTMTKGSE 119
            |:||.||.| |.|.:||..||::..:...:|:.|      |....||:.:||..||.:.:...::
 Frog    60 SYGNICGQK-NTKIEGFVNSGLDHSNHKYVFFLDPCKLDLVNRKIKSIALCVSECPREELQTLND 123

  Fly   120 LLEYYSQTGTQLCKYDYNMQQLTTAGNDAKTFNFLGPCPSFPVHESSPV--LHRCVPKGT---GE 179
            :.::....|:.||.|.....|.||..:.:..      ||..||.:|:|:  .|||.|...   .:
 Frog   124 VKKFAETNGSALCDYSLTPSQYTTDSSASSL------CPKLPVPKSAPIPFFHRCAPVNISCYAK 182

  Fly   180 KVQNYYDMLNNWDVAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVIVA 244
            ..:.....:::..|..:.:..:.::..||..:|.|:|::|:.|:.::.::||::.|||.:||::.
 Frog   183 FAEALITFVSDNSVLHRLISGVMTSKEIIMGLCLLSLVLSMILMVIIRYISRVLVWIITILVVLG 247

  Fly   245 SVALTVALWYAYYNIRNKSGVNTQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKLAG 309
            |:..|..||:.|.:.:.....|.....|:....|.||:|..|:.||:..:||::::..::.::|.
 Frog   248 SLGGTGVLWWLYADKKKSFNENLPPDQLQVSKDNLQALLVYAIAATVFTVILLLMMLIMRKRVAL 312

  Fly   310 LSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAHQQ 374
            ..|||..||:..::||.|:..|...|..|:.|..:||.|::.|.||..|
 Frog   313 TIALFHVAGKVFIHLPLLVFQPFWTFFALLLFWVYWVMVLLFLGTAGDP---------------- 361

  Fly   375 PLPANALFVSNSTDVNDLRPNARVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVAFW 439
                       ||:....     ||:...|.|:.|:|.::|||||..|||.||||..:|.||..:
 Frog   362 -----------STNEQGF-----VEFRINGPLQYMWWYHLVGLIWISEFILACQQMTIAGAVVTY 410

  Fly   440 YFQKPTS----TPTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSECAA 500
            ||.:..:    ||...::.:|::|||||||||:|:||:.||||:||.|::::||   .|.:.||.
 Frog   411 YFTRNKNDLPFTPILASVNRLIRYHLGTVAKGAFIITLVKIPRMILMYIHSQLK---GKENACAR 472

  Fly   501 CCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFILF 565
            |.||.|||..|.|||.:.:||.||||..||.|.|||.:|..|...:..|||:||.||:||||:||
 Frog   473 CMLKSCICCLWCLEKCLAYLNQNAYTATAINSTNFCTSAKDALVILVENVLRVAAINTVGDFMLF 537

  Fly   566 LGKVVVAALSGLIGIVLLKDKPGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCEDKT 630
            |||:::.:.:||.|::||..:.....::.|:||:.:|:|.:||..||::|||||.||||...|..
 Frog   538 LGKILIVSSTGLAGVMLLNYQRDYTVWVLPLIIVCLFAFLVAHCFLSIYEMVVDVLFLCFAIDTK 602

  Fly   631 LNGRSGRWAQSNLAKLVGEEPLQPGEEPPIEVVQMMPIN------KQPFSITRLPQSDPEVAPMS 689
            .|..|                  ||:|..::.|.|..:.      |:|.|..    ...|:.||:
 Frog   603 YNDGS------------------PGKEFYMDKVLMEFVENSRRAMKEPGSAA----EGRELKPMA 645

  Fly   690 A 690
            :
 Frog   646 S 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	DUF4481	<207..>316	CDD:291466	34/108 (31%)
		Choline_transpo	286..629	CDD:282384	140/346 (40%)
slc44a1	XP_002934036.2	Choline_transpo	290..600	CDD:367975	139/344 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	264	1.000	Domainoid score	I1881
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11137
Inparanoid	1	1.050	399	1.000	Inparanoid score	I1887
OMA	1	1.010	-	-		QHG45602
OrthoDB	1	1.010	-	-		D167290at33208
OrthoFinder	1	1.000	-	-		FOG0000381
OrthoInspector	1	1.000	-	-		otm48984
Panther	1	1.100	-	-	LDO	PTHR12385
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2976
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.080