Protein Alignment Ctl1 and slc44a1a

DIOPT Version :9

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_002660627.2
• Gene: slc44a1a / 100333377
• ZFINID: ZDB-GENE-050417-204
• Length: 651
• Species: Danio rerio
• Alignment Length: 660
• Identity: 235/660 - (35%)
• Similarity: 362/660 - (54%)
• Gaps: 73/660 - (11%)

  Fly     1 MGCAESKDGEGEAQNNRP----KYRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDS 61
            |||.      |..|..|.    :.|.|||..||.::|:|.:.::.|..|:...|...|:::||||
Zfish     1 MGCC------GSTQKERDWKPLEQRRCTDIPWLLLFILFNIGMLCICGFAIATGAATRLVSGYDS 59

  Fly    62 FGNTCGVKYNEKFQGFPLSGMNTLDKPELFYFD------VKELKKSLKICVKSCPAKTMTKGSEL 120
            :|||||.| |.:..|...||::..::..:|:.|      .|...||:.:||..||...:....:|
Zfish    60 YGNTCGQK-NAQIPGIEHSGLDHSNRKYVFFLDPCKIDIAKRKIKSVALCVSKCPKVQLDTYEDL 123

  Fly   121 LEYYSQTGTQLCKYDYNMQQLTTAGN-DAKTFNFLGPCPSFPVHESS--PVLHRCVPK-----GT 177
            .::.:..|:.||.||...:..::..| |.|       ||..||..|:  ||.|||:|.     .|
Zfish   124 TKFATVNGSALCTYDVQPEAYSSNPNKDVK-------CPKLPVFPSASLPVFHRCMPVDISCFAT 181

  Fly   178 GEKVQNYYDMLNNWDVAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVI 242
            ..|.  :...:::..|..:.:..:.....||..:|.|||::|:.|:.::.::|.::.||:..:|:
Zfish   182 FAKA--FITFVSDNSVLHRVIAGVMMAKEIIMGLCLLALVLSLILMVVIRYISVLLVWILTAVVV 244

  Fly   243 VASVALTVALWYAYYNIRNKSGVNTQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKL 307
            :.||.....||:.|.:.............||....||||:|..|:.|||..::|:::::|::.::
Zfish   245 IGSVGGCGILWWLYVDQGKALNATMPAHDLEIAHDNQQALLIYAIGATIFTVLLLLLMFFMRKRV 309

  Fly   308 AGLSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAH 372
            |...|||..||:...:||.|.:.|...||.|:.|..:|::|::||.||.||.:
Zfish   310 ALTIALFHVAGKVFTHLPLLALQPFWTFLTLMLFWVYWISVLLCLGTAGSPVK------------ 362

  Fly   373 QQPLPANALFVSNSTDVNDLRPNARVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVA 437
                       :|.|.:        ||:...|.|:.|.|.:.|||||..|||.||||..:|.||.
Zfish   363 -----------NNRTGL--------VEFKMDGPLQYMVWYHAVGLIWVSEFILACQQMTIAGAVV 408

  Fly   438 FWYFQKPTS----TPTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSEC 498
            .:||.:..|    ||...::.:|:::||||||||:|:||:.:||||||||::::||   .|.:.|
Zfish   409 TYYFTRDKSQLPFTPIVSSVLRLMRFHLGTVAKGAFIITLVEIPRLILTYIHSQLK---GKENAC 470

  Fly   499 AACCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFI 563
            |.|.||.|||..|.|||.:.:||.||||..||.|.|||.:|..|...:|.|.|:||.|||||||:
Zfish   471 ARCMLKACICCLWCLEKCLSYLNMNAYTATAINSTNFCTSARDALFILAENALRVAAINSVGDFV 535

  Fly   564 LFLGKVVVAALSGLIGIVLLKDKPGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCED 628
            |||||:::.:.:...|::.|..:...:.::.|:||:.:|:|.:||..||:||:|||.||||...|
Zfish   536 LFLGKILIVSCTAFAGVLSLNYQREYSVWVLPLIIVCVFAFLVAHCFLSVFEIVVDVLFLCFAID 600

  Fly   629 -KTLNGRSGR 637
             |..:|..||
Zfish   601 TKQNDGSPGR 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	DUF4481	<207..>316	CDD:291466	34/108 (31%)
		Choline_transpo	286..629	CDD:282384	143/347 (41%)
slc44a1a	XP_002660627.2	Choline_transpo	288..600	CDD:282384	142/345 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595056
Domainoid	1	1.000	268	1.000	Domainoid score	I1817
eggNOG	1	0.900	-	-		E1_KOG1362
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11137
Inparanoid	1	1.050	396	1.000	Inparanoid score	I1914
OMA	1	1.010	-	-		QHG45602
OrthoDB	1	1.010	-	-		D167290at33208
OrthoFinder	1	1.000	-	-		FOG0000381
OrthoInspector	1	1.000	-	-		otm26241
orthoMCL	1	0.900	-	-		OOG6_104769
Panther	1	1.100	-	-	O	PTHR12385
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4525
SonicParanoid	1	1.000	-	-		X2976
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800