Protein Alignment Ctl1 and slc44a1a

DIOPT Version :10

• Sequence 1: NP_647884.1
• Gene: Ctl1 / 38523
• FlyBaseID: FBgn0035523
• Length: 691
• Species: Drosophila melanogaster
• Sequence 2: XP_002660627.2
• Gene: slc44a1a / 100333377
• ZFINID: ZDB-GENE-050417-204
• Length: 651
• Species: Danio rerio
• Alignment Length: 660
• Identity: 235/660 - (35%)
• Similarity: 362/660 - (54%)
• Gaps: 73/660 - (11%)

  Fly     1 MGCAESKDGEGEAQNNRP----KYRSCTDTCWLAIYIIFWLFLIVIAIFSFVYGNPLRIINGYDS 61
            |||.      |..|..|.    :.|.|||..||.::|:|.:.::.|..|:...|...|:::||||
Zfish     1 MGCC------GSTQKERDWKPLEQRRCTDIPWLLLFILFNIGMLCICGFAIATGAATRLVSGYDS 59

  Fly    62 FGNTCGVKYNEKFQGFPLSGMNTLDKPELFYFD------VKELKKSLKICVKSCPAKTMTKGSEL 120
            :|||||.| |.:..|...||::..::..:|:.|      .|...||:.:||..||...:....:|
Zfish    60 YGNTCGQK-NAQIPGIEHSGLDHSNRKYVFFLDPCKIDIAKRKIKSVALCVSKCPKVQLDTYEDL 123

  Fly   121 LEYYSQTGTQLCKYDYNMQQLTTAGN-DAKTFNFLGPCPSFPVHESS--PVLHRCVPK-----GT 177
            .::.:..|:.||.||...:..::..| |.|       ||..||..|:  ||.|||:|.     .|
Zfish   124 TKFATVNGSALCTYDVQPEAYSSNPNKDVK-------CPKLPVFPSASLPVFHRCMPVDISCFAT 181

  Fly   178 GEKVQNYYDMLNNWDVAQQFVGDIYSTWHIIAMVCGLALLISIALVTMMHWLSRIVSWIICVLVI 242
            ..|.  :...:::..|..:.:..:.....||..:|.|||::|:.|:.::.::|.::.||:..:|:
Zfish   182 FAKA--FITFVSDNSVLHRVIAGVMMAKEIIMGLCLLALVLSLILMVVIRYISVLLVWILTAVVV 244

  Fly   243 VASVALTVALWYAYYNIRNKSGVNTQYSMLEEFVRNQQAVLTLAVLATITMIILIVVIYFLKNKL 307
            :.||.....||:.|.:.............||....||||:|..|:.|||..::|:::::|::.::
Zfish   245 IGSVGGCGILWWLYVDQGKALNATMPAHDLEIAHDNQQALLIYAIGATIFTVLLLLLMFFMRKRV 309

  Fly   308 AGLSALFEEAGQCMMNLPGLLIAPLLAFLVLIAFLSFWVAVIICLATASSPGQSPIAPFDNSKAH 372
            |...|||..||:...:||.|.:.|...||.|:.|..:|::|::||.||.||.:
Zfish   310 ALTIALFHVAGKVFTHLPLLALQPFWTFLTLMLFWVYWISVLLCLGTAGSPVK------------ 362

  Fly   373 QQPLPANALFVSNSTDVNDLRPNARVEYADAGVLRSMFWIYVVGLIWTVEFIFACQQFALAAAVA 437
                       :|.|.:        ||:...|.|:.|.|.:.|||||..|||.||||..:|.||.
Zfish   363 -----------NNRTGL--------VEFKMDGPLQYMVWYHAVGLIWVSEFILACQQMTIAGAVV 408

  Fly   438 FWYFQKPTS----TPTFYAIGKLVKYHLGTVAKGSFVITIFKIPRLILTYLYAKLKKGEDKGSEC 498
            .:||.:..|    ||...::.:|:::||||||||:|:||:.:||||||||::::||   .|.:.|
Zfish   409 TYYFTRDKSQLPFTPIVSSVLRLMRFHLGTVAKGAFIITLVEIPRLILTYIHSQLK---GKENAC 470

  Fly   499 AACCLKCCICGFWLLEKFIRFLNHNAYTVVAIESINFCPAAGIAWNAMATNVLQVATINSVGDFI 563
            |.|.||.|||..|.|||.:.:||.||||..||.|.|||.:|..|...:|.|.|:||.|||||||:
Zfish   471 ARCMLKACICCLWCLEKCLSYLNMNAYTATAINSTNFCTSARDALFILAENALRVAAINSVGDFV 535

  Fly   564 LFLGKVVVAALSGLIGIVLLKDKPGLNFYMAPVIIIIIFSFFIAHIILSLFEMVVDTLFLCVCED 628
            |||||:::.:.:...|::.|..:...:.::.|:||:.:|:|.:||..||:||:|||.||||...|
Zfish   536 LFLGKILIVSCTAFAGVLSLNYQREYSVWVLPLIIVCVFAFLVAHCFLSVFEIVVDVLFLCFAID 600

  Fly   629 -KTLNGRSGR 637
             |..:|..||
Zfish   601 TKQNDGSPGR 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ctl1	NP_647884.1	Choline_transpo	287..629	CDD:461337	142/346 (41%)
slc44a1a	XP_002660627.2	Choline_transpo	289..600	CDD:461337	141/344 (41%)