DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1273 and Fndc1

DIOPT Version :9

Sequence 1:	NP_647883.1	Gene:	CG1273 / 38522	FlyBaseID:	FBgn0035522	Length:	1168	Species:	Drosophila melanogaster
Sequence 2:	XP_006227933.1	Gene:	Fndc1 / 308099	RGDID:	1310640	Length:	1831	Species:	Rattus norvegicus

Alignment Length:	530	Identity:	117/530 - (22%)
Similarity:	166/530 - (31%)	Gaps:	199/530 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   210 RKLP----QNILSVEEYIKESLF------LETSAAK--------SLYRSLRLDTESVEIKRIMDE 256
            |.||    |::.:.||...|.:.      |.||..|        ..|....||.:...|
  Rat  1108 RPLPLESQQSVFAEEEEENEGMLKGKEDSLSTSVKKWPSSSSPRDKYADRNLDKDKAAI------ 1166

  Fly   257 QVVRSAAILKEAQTVPTSQTQLEKRLMKKGSTPATPPVHPKPNPNTTPKPKNPLLRSHSADEEPD 321
                 ..:::|..|||..:            .|.:|.:  ..:|:|..:|:||      |...|.
  Rat  1167 -----GLLVQEENTVPGRR------------PPGSPAI--ASHPSTRHQPRNP------ATASPI 1206

  Fly   322 IDVENAPVIQGSFEGSFEIT------------KTDADIARKKTPP----TRAYQA---ASSTLPP 367
            .:..:.|........|:..|            :....::|:..||    |..|..   |...:||
  Rat  1207 ANTHSWPRYTTRAPSSYSSTTPMLSLRQRMQRRFRTPVSRQPPPPRPVLTPGYNGRPNAEENIPP 1271

  Fly   368 KAIAV-------------------------------------TPFSLRVKPKKPSIEKL---TTV 392
            .:|..                                     .|..:|:.....:|..|   ..|
  Rat  1272 GSIGKPNGQRIINGPQGTKWVVDLDRGLVLNAEGRYLQDSHGNPLRVRLGGDGRTIVDLGGTPMV 1336

  Fly   393 LPQQLPT------GGPISSTR---------ATTKATKATTTTTKRTTTSTTRKTTTTTTPKPTTT 442
            .|..||.      |.|::|.:         ......:...|||:..||:....|||||.| ||||
  Rat  1337 SPDGLPLFGQGRHGKPVASAQDKPILSLGGKPLVGLEVVRTTTQVPTTTMPPSTTTTTVP-PTTT 1400

  Fly   443 ---TTTTEATTTTTTSTTTTTPPLPPSTTRATTTSTNTFTYPSVNTPPP----------NQGGSL 494
               ||||...||||..||||.  .|.:|||||..:|.|.|.|...||.|          ::.|:|
  Rat  1401 LPPTTTTTRRTTTTRRTTTTR--RPTTTTRATRRTTTTTTTPEPTTPSPTCPPGTLEHRDEAGNL 1463

  Fly   495 -------PKL---------------------------DANLFTTFPILDTQPWRPMHREVPELLP 525
                   |:.                           |..|.||.|...|.|  ......|:::|
  Rat  1464 IMGSNGIPECYPEEDDFSGLEIDTALPTEEDYVVYDDDYGLETTRPPTSTMP--STTAATPKVVP 1526

  Fly   526 --GPPPAFPTK----------------------TLPGGTTPTVNHIPQRRIDEFELPFIADNPTP 566
              |...:||.:                      ..|...|..::|.....:||.....:..|..|
  Rat  1527 EQGTVSSFPEEEFDLAGKRRFVAPYVTYLSKDPAAPCSLTDALDHFQVESLDELIPNDLTKNDLP 1591

  Fly   567 PTAAVAPVTV 576
            |..|...:||
  Rat  1592 PQHAPRNITV 1601

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1273	NP_647883.1	None
Fndc1	XP_006227933.1	FN3	37..117	CDD:214495
		FN3	155..238	CDD:214495
		FN3	258..351	CDD:238020
		fn3	359..444	CDD:278470
		Treacle	530..1059	CDD:281536
		FN3	1595..1686	CDD:238020	3/7 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23197
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100