DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1309 and abhd12

DIOPT Version :9

Sequence 1:	NP_647880.1	Gene:	CG1309 / 38519	FlyBaseID:	FBgn0035519	Length:	524	Species:	Drosophila melanogaster
Sequence 2:	NP_001070065.1	Gene:	abhd12 / 767657	ZFINID:	ZDB-GENE-060929-268	Length:	382	Species:	Danio rerio

Alignment Length:	255	Identity:	46/255 - (18%)
Similarity:	101/255 - (39%)	Gaps:	59/255 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 GIRYKVKTIDSNEIDTLFIDNRPNNVGNGKTLVICSEGNAGF----YEVGIMATPVALKYSVLGW 274
            |:..:.:..|:...:..|..:.|        :::...||||.    :.|.:.....:|.|.|:.:
Zfish   133 GMWREAQAKDAEWYEKSFQSSHP--------VILYLHGNAGTRGGDHRVQLYKVLSSLGYHVVTF 189

  Fly   275 NHPGFAGSTGTPHPHQDKNAIDAVVQFAINNLRFPVEDIILYGWSIG-GFST-----LYAASVYP 333
            ::.|:..|.|:  |.:.....||:..:.....|...:.:.::|.|:| |.:|     |......|
Zfish   190 DYRGWGDSEGS--PSERGMTSDALFLYQWIKQRIGPKPLYIWGHSLGTGVATNLVRRLCDRGTPP 252

  Fly   334 DVKGVVLDATFDDV-----------LYLAVPR-----MPAALAGIVKVAIRNYCNLNNAELANEF 382
            |  .::|::.|.::           :|..:|.     :.|..|..::.|        :.|..|..
Zfish   253 D--ALILESPFTNIREEAKSHPFSMVYRYLPGFDWFFLDAISANDIRFA--------SDENVNHI 307

  Fly   383 NGPISFIRRTEDEII------------AEDNHIDTNRGNFLVL-SVLKHRYPNIFGASQL 429
            :.|:..:...:|.::            |:...::.::..|:.. |.|.:|:..|:.:.||
Zfish   308 SCPVLILHAEDDTVVPFQLGKKLYDLAAQSKSLNGHKVQFIPFSSSLGYRHKFIYKSPQL 367

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1309	NP_647880.1	Abhydrolase_5	245..>356	CDD:289465	27/136 (20%)
abhd12	NP_001070065.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..45
abhd12	NP_001070065.1	Hydrolase_4	151..340	CDD:378820	36/208 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594466
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.840