DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15011 and stc

DIOPT Version :9

Sequence 1:	NP_647879.1	Gene:	CG15011 / 38518	FlyBaseID:	FBgn0035518	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_476599.1	Gene:	stc / 34888	FlyBaseID:	FBgn0001978	Length:	1106	Species:	Drosophila melanogaster

Alignment Length:	859	Identity:	257/859 - (29%)
Similarity:	354/859 - (41%)	Gaps:	221/859 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 NKAQAKNLAAAQKLVDTYASSSEDEGELDENHILELLYKNYKPSDNAGSSKEAARTSTFLENTLH 69
            |:.:......|...:||...|:....| .::.:.::..:...|...|.:.|.:.|..  |...:.
  Fly   319 NRDRINGFPRAVDDLDTSNESAHPSPE-KQSQLQQISPRRGPPLPPADNEKLSQREK--LVRDIE 380

  Fly    70 SGAATCLICIGSIRRVEAIWSCESCYCFFHLKCIQRWANDSMMQMKVKAAEQQNGQGHYNHLGEF 134
            .....||:|:.:|:..:..|||.:||...||||...||:.|
  Fly   381 QRRLECLVCVEAIKSHQPTWSCRNCYHMLHLKCTITWASSS------------------------ 421

  Fly   135 VPPKRQKSLHWCCPKCRRDYQPADKPTQYNCFCGKEVNPENQPFLVPHSCGEHCGKLLQPKCGHD 199
                 :..:.|.||.|:...|  |.|..|.|||||..||......:.|||||.|.::  ..|.|.
  Fly   422 -----KSEVGWRCPACQNVLQ--DLPRDYLCFCGKLKNPPVSRTELAHSCGEVCCRI--EGCSHA 477

  Fly   200 CKLLCHPGPCPPCAQQAQVSCLCGKSSPRSVRCIDKQWT-CQQTCKELLACGKHKCNQVCHQPGK 263
            |.|||||||||||......||.||:|: ::::|..|:.. |.:.|.:||.||:|:|...||. ||
  Fly   478 CTLLCHPGPCPPCQANVVRSCGCGRST-KTMQCAMKEEVLCGEICDKLLNCGEHRCQAECHS-GK 540

  Fly   264 CPPCTSKSLQPCECQRESKMVNCS-----DRKWKCQNVCGAPFACGLHICEKVCHAGPCGDGEC- 322
            |..|:.:.:|.|.|.::.:.|.|:     .|.:.|::.||.|..||.|.|:..||||.|  ..|
  Fly   541 CAACSEQVVQQCHCGKQERKVPCTRESQDKRTYSCKDSCGQPLPCGHHKCKDSCHAGSC--RPCK 603

  Fly   323 --PLQVRSCPCGKNT----QVRPCNETEETCGDTCQKLLSCGQ----HTCTQRCHRGPCISCPIR 377
              |.|:.||||||..    |...|.:...||...|.:.|.||:    |.|..:||.|.|..||.:
  Fly   604 LSPEQITSCPCGKMPVPAGQRSSCLDPIPTCEGICSRTLRCGKPAHPHQCGSKCHLGQCPPCPKQ 668

  Fly   378 TKKKCRCGLHEKELPC------SKEFACETKCKQMRDCGKHACNRKCCGDQCPPCEKICGKQLSC 436
            |..|||||..::.:.|      :.:..|:.:|.:.|.||||.||.:||.|....|...|.:.|||
  Fly   669 TGVKCRCGHMDQMIKCRQLCNRADDARCKRRCTKKRSCGKHKCNVECCIDIDHDCPLPCNRTLSC 733

  Fly   437 NKHKCQSVCHNGPCYPCKLES--QINCRCGK--TKKSVPCGRERSARIVC-LELCRITPKCHHAI 496
            .||||...||.|.|.||...|  ::.|.||.  ....||||.::.   :| |...||.| |.|..
  Fly   734 GKHKCDQPCHRGNCPPCYRSSFEELYCECGAEVIYPPVPCGTKKP---ICKLPCSRIHP-CDHPP 794

  Fly   497 KHRCHKG-DCPPCGQVCGLPNDTSKCGHICKARCHEAVRVNKPKEARPQAKKYEYKALPHPRCEE 560
            :|.||.| .||||
  Fly   795 QHNCHSGPTCPPC---------------------------------------------------- 807

  Fly   561 GVIVT---CIGGHEV-ATWPCWNSKPT-SCQRSCARQLKCGNHKCSLVCHFVPLPQDMSAQTGCA 620
             :|.|   |.|.||: .|.||  |:|. ||..:|.:.|.||.|||...||..|      .|:...
  Fly   808 -MIFTTKLCHGNHELRKTIPC--SQPNFSCGMACGKPLPCGGHKCIKPCHEGP------CQSAGE 863

  Fly   621 NCEEGCTVPRPTGCIHACPKGCHPPPC--APCNFVIKTKCHCGLNQLVYKCNEYYDETGSVQEII 683
            .|.:.||.|||| |.|.|...||...|  .||..:::.:|.||
  Fly   864 ICRQSCTKPRPT-CGHKCAAACHEGACPETPCKELVEVQCECG---------------------- 905

  Fly   684 ERREKLRSCGNRCLKNYPCGHRCTAICHTGKCPNPELCRKKVRIFCACKRLK------------- 735
             .|::.|||                         .||.|:..||  |..:|.
  Fly   906 -NRKQNRSC-------------------------QELAREHSRI--ATIQLASSMAEMSRGNYME 942

  Fly   736 -QEIACDKHRAGQTFLDCDSNCK-AEQIRVQAAEQLQLEQKRRDEEERNRLELEKFEAKFGKRKH 798
             .||.....::.:| |||:..|: .|:.|..||   .|.....|.:::...:..:|...|.|:
  Fly   943 LSEILAPAKKSNKT-LDCNDECRLLERNRRLAA---ALSSGNSDTKQKCLTKYSEFVRGFAKK-- 1001

  Fly   799 KERKTVGSGPAKTK 812
                    .||.||
  Fly  1002 --------NPALTK 1007

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15011	NP_647879.1	NF-X1-zinc-finger	184..228	CDD:100116	23/43 (53%)
		NF-X1-zinc-finger	239..288	CDD:100116	19/53 (36%)
		NF-X1-zinc-finger	293..342	CDD:100116	24/55 (44%)
		NF-X1-zinc-finger	347..395	CDD:100116	20/57 (35%)
		NF-X1-zinc-finger	426..474	CDD:100116	22/51 (43%)
		NF-X1-zinc-finger	692..740	CDD:100116	10/61 (16%)
stc	NP_476599.1	NF-X1-zinc-finger	464..510	CDD:100116	23/48 (48%)
		NF-X1-zinc-finger	517..565	CDD:100116	19/48 (40%)
		NF-X1-zinc-finger	575..617	CDD:100116	21/43 (49%)
		NF-X1-zinc-finger	634..686	CDD:100116	20/51 (39%)
		NF-X1-zinc-finger	723..775	CDD:100116	22/51 (43%)
		NF-X1-zinc-finger	834..882	CDD:100116	22/54 (41%)
		NF-X1-zinc-finger	865..915	CDD:100116	22/98 (22%)
		R3H_NF-X1	996..1069	CDD:100072	6/22 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45462296
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1952
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D22067at50557
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR12360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850