DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1265 and slc66a3

DIOPT Version :9

Sequence 1:	NP_647878.1	Gene:	CG1265 / 38517	FlyBaseID:	FBgn0035517	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_001004615.1	Gene:	slc66a3 / 447876	ZFINID:	ZDB-GENE-040912-40	Length:	203	Species:	Danio rerio

Alignment Length:	199	Identity:	61/199 - (30%)
Similarity:	100/199 - (50%)	Gaps:	22/199 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 TVSSCLVIKVPQINTIRANESSKGISVLGLCLELFSYTVMLSYNYTSGYDFLSYMEYPVLLLQEY 93
            |:..|:|:|.|||..:....::.|:|:..|.|||..:.|.:||.....|..|:|:|||:|:.|:.
Zfish    14 TLFVCMVLKFPQIFVLLRARAAAGVSLNSLLLELLGFIVFMSYQMYYEYPPLTYLEYPILIAQDV 78

  Fly    94 ALIYYAFKYQDLLGRRTQVVAILYSIVATLIYMKLFP-----IIILKFLV----PFCTPIGATSK 149
            .::.....|.             .::..:|||..||.     :.:.|:::    ..||.|..:||
Zfish    79 IVLLLILHYN-------------RNLKHSLIYAALFVGGWQLLTVKKWVIDLAMSLCTLISGSSK 130

  Fly   150 VLQLLAILRTKDASSVSRTTWALSAFTNMTRIYTVFFQSHDWMLLSNFLISTFLSASVFTAACVY 214
            :.||..:.|:||:..||..||||:.:|.|.||:|....:.|..:|..|::.|.|:..|......|
Zfish   131 LAQLQCLWRSKDSGQVSSLTWALATYTCMARIFTTIITTGDTQVLVRFIVMTILNMWVTATVIYY 195

  Fly   215 KKKA 218
            |.:|
Zfish   196 KPQA 199

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1265	NP_647878.1	PQ-loop	22..80	CDD:282099	17/50 (34%)
slc66a3	NP_001004615.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593604
Domainoid	1	1.000	73	1.000	Domainoid score	I9252
eggNOG	1	0.900	-	-		E1_KOG3211
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16454
Inparanoid	1	1.050	103	1.000	Inparanoid score	I4945
OMA	1	1.010	-	-		QHG47627
OrthoDB	1	1.010	-	-		D1059579at2759
OrthoFinder	1	1.000	-	-		FOG0008406
OrthoInspector	1	1.000	-	-		oto40853
orthoMCL	1	0.900	-	-		OOG6_110752
Panther	1	1.100	-	-	LDO	PTHR12226
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5753
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	15	14.800