DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1265 and SLC66A3

DIOPT Version :9

Sequence 1:	NP_647878.1	Gene:	CG1265 / 38517	FlyBaseID:	FBgn0035517	Length:	221	Species:	Drosophila melanogaster
Sequence 2:	NP_689604.1	Gene:	SLC66A3 / 130814	HGNCID:	28503	Length:	202	Species:	Homo sapiens

Alignment Length:	204	Identity:	72/204 - (35%)
Similarity:	110/204 - (53%)	Gaps:	8/204 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 ADLLSLI---TVSSCLVIKVPQINTIRANESSKGISVLGLCLELFSYTVMLSYNYTSGYDFLSYM 83
            |.||.|.   |:..|..:|:|||:.:.|..|::|:|:..|.|||..:.|.|.|....||..|:|:
Human     3 AALLGLCNWSTLGVCAALKLPQISAVLAARSARGLSLPSLLLELAGFLVFLRYQCYYGYPPLTYL 67

  Fly    84 EYPVLLLQEYALIYYAFKYQDLLGRRTQVVAILYSIVATLIYMKLFPIIILKFLVPFCTPIGATS 148
            |||:|:.|:..|:...|.:...:.:.|..:|:|.|....|...|.    |:...:..||.|.|.|
Human    68 EYPILIAQDVILLLCIFHFNGNVKQATPYIAVLVSSWFILALQKW----IIDLAMNLCTFISAAS 128

  Fly   149 KVLQLLAILRTKDASSVSRTTWALSAFTNMTRIYTVFFQSHDWMLLSNFLISTFLSASVFTAACV 213
            |..||..:.:|:|:.:||..||:||::|..|||.|....::|:.:|..|:|...|:..|......
Human   129 KFAQLQCLWKTRDSGTVSALTWSLSSYTCATRIITTLMTTNDFTILLRFVIMLALNIWVTVTVLR 193

  Fly   214 YKKKA-KAE 221
            |:|.| |||
Human   194 YRKTAIKAE 202

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1265	NP_647878.1	PQ-loop	22..80	CDD:282099	23/60 (38%)
SLC66A3	NP_689604.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165157813
Domainoid	1	1.000	78	1.000	Domainoid score	I8837
eggNOG	1	0.900	-	-		E1_KOG3211
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H16454
Inparanoid	1	1.050	114	1.000	Inparanoid score	I4845
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG47627
OrthoDB	1	1.010	-	-		D1059579at2759
OrthoFinder	1	1.000	-	-		FOG0008406
OrthoInspector	1	1.000	-	-		oto88873
orthoMCL	1	0.900	-	-		OOG6_110752
Panther	1	1.100	-	-	LDO	PTHR12226
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5753
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.800