DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ago and fbxo16

DIOPT Version :9

Sequence 1:	NP_523922.1	Gene:	ago / 38516	FlyBaseID:	FBgn0041171	Length:	1326	Species:	Drosophila melanogaster
Sequence 2:	NP_001017680.1	Gene:	fbxo16 / 550375	ZFINID:	ZDB-GENE-041015-747	Length:	348	Species:	Danio rerio

Alignment Length:	263	Identity:	61/263 - (23%)
Similarity:	110/263 - (41%)	Gaps:	59/263 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   845 LQHWLAQFQRWSHVERLLALDRLIDHCDPSQVRHMMKVIE---PQFQRDFISLLPRELALFVLSY 906
            |..|   |::|:..:|...|......|...|::|:.:.:.   |:...||.::|||.::|::.||
Zfish    28 LGKW---FEKWTDSQRKQVLQDFFSRCSAGQLKHLRQTLSSWVPEETLDFTTVLPRVISLYIFSY 89

  Fly   907 LEPKDLLRAAQTCRSWRFLCDDNLLWKEKCRKAQ--ILAEPRSDRPKRGRDGNMPPIASPWKAAY 969
            |:|:.|.|.||....|:.|.:.:.||..||.|..  |...|            .|.....||..|
Zfish    90 LDPRSLCRCAQVSWHWKNLAELDQLWMPKCLKLGWCITFTP------------TPFEQGVWKRQY 142

  Fly   970 MRQHIIEMNWRSRPVRKPKV-LKGHDDHVITCLQFSGNRIVSGSDDNTLKVWSAVNGKCLRTLVG 1033
            : :.:.|::     :.:||| :|  ::.::..:     :::....:.:|            .|.|
Zfish   143 I-ETVQELH-----ISRPKVPVK--EEFIVPDV-----KVIGSETEGSL------------PLTG 182

  Fly  1034 HTG--GVWSSQMSGNIIISGSTDRTLKVW-DMDSGACVHTLQGHTSTVRCMHLHGSKVVSGSRDA 1095
            |..  |:.....:||.:  |.:.:.|..| |.|        :..|.|:|..:|........:|.|
Zfish   183 HRDLLGLQGRSKNGNDL--GKSAKGLPPWRDSD--------RHPTDTIRFNYLDNLHPGEHARKA 237

  Fly  1096 TLR 1098
            .|:
Zfish   238 LLK 240

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ago	NP_523922.1	F-box-like	892..938	CDD:289689	18/45 (40%)
		WD40	<981..1274	CDD:225201	23/122 (19%)
		WD40	988..1264	CDD:238121	22/115 (19%)
		WD40 repeat	998..1033	CDD:293791	2/34 (6%)
		WD40 repeat	1039..1073	CDD:293791	7/34 (21%)
		WD40 repeat	1078..1112	CDD:293791	5/21 (24%)
		WD40 repeat	1119..1152	CDD:293791
		WD40 repeat	1158..1192	CDD:293791
		WD40 repeat	1200..1232	CDD:293791
		WD40 repeat	1241..1263	CDD:293791
fbxo16	NP_001017680.1	F-box-like	78..121	CDD:289689	18/42 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.000