DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ago and Fbxo16

DIOPT Version :9

Sequence 1:	NP_523922.1	Gene:	ago / 38516	FlyBaseID:	FBgn0041171	Length:	1326	Species:	Drosophila melanogaster
Sequence 2:	NP_001013150.1	Gene:	Fbxo16 / 305970	RGDID:	1305049	Length:	334	Species:	Rattus norvegicus

Alignment Length:	149	Identity:	41/149 - (27%)
Similarity:	68/149 - (45%)	Gaps:	26/149 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   845 LQHWLAQFQRWSHVERLLALDRLIDHCDPSQVRHMMKVIE---PQFQRDFISLLPRELALFVLSY 906
            |..|   |.:|:..:|...|..|::.|..||.:...:.::   |....||.:.|||.|::::.|:
  Rat    42 LGKW---FDKWTDSQRRRILTGLLERCSLSQQKFCCRKLQEKIPAEALDFTTKLPRVLSVYIFSF 103

  Fly   907 LEPKDLLRAAQTCRSWRFLCDDNLLWKEKCRKAQ--ILAEPRSDRPKRGRDGNMPPIASPWKAAY 969
            |:|:.|.|.||....|:.|.:.:.||..||.:..  |...|                 :|::...
  Rat   104 LDPRSLCRCAQVSWYWKSLAELDQLWMLKCLRFNWYISFSP-----------------TPFEQGV 151

  Fly   970 MRQHIIEMNWRSRPVRKPK 988
            .::|.|:| .|...|.|||
  Rat   152 WKKHYIQM-VRELHVTKPK 169

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ago	NP_523922.1	F-box-like	892..938	CDD:289689	17/45 (38%)
		WD40	<981..1274	CDD:225201	4/8 (50%)
		WD40	988..1264	CDD:238121	1/1 (100%)
		WD40 repeat	998..1033	CDD:293791
		WD40 repeat	1039..1073	CDD:293791
		WD40 repeat	1078..1112	CDD:293791
		WD40 repeat	1119..1152	CDD:293791
		WD40 repeat	1158..1192	CDD:293791
		WD40 repeat	1200..1232	CDD:293791
		WD40 repeat	1241..1263	CDD:293791
Fbxo16	NP_001013150.1	F-box-like	92..129	CDD:403981	13/36 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0274
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900