Protein Alignment ago and fbxw8

DIOPT Version :9

• Sequence 1: NP_523922.1
• Gene: ago / 38516
• FlyBaseID: FBgn0041171
• Length: 1326
• Species: Drosophila melanogaster
• Sequence 2: XP_017946093.1
• Gene: fbxw8 / 100294668
• XenbaseID: XB-GENE-991104
• Length: 657
• Species: Xenopus tropicalis
• Alignment Length: 585
• Identity: 131/585 - (22%)
• Similarity: 208/585 - (35%)
• Gaps: 179/585 - (30%)

  Fly   820 SSTPGSALGRRTPRSVPSRDNPPPELQHWLAQFQRWSHV--------------------ERLLA- 863
            :||.....|.|..|.  |..:|.||.||  .:.:.|.::                    ||||.
 Frog    21 ASTSAERSGTRKRRR--SGQSPEPEKQH--NEGEAWRYLPGSPERSSAEEQGNQYVELAERLLGD 81

  Fly   864 ------------------------LDRLIDHCDPSQVRHMMKVIEPQFQRDFISLLPRELALFVL 904
                                    :|:|||  |.:.:..:     |.|...    ||.|:||.:.
 Frog    82 QGSATESAQRPSAGPAQEERARSLVDQLID--DLNDINEI-----PFFDIQ----LPYEIALQIF 135

  Fly   905 SYLEPKDLLRAAQTCRSWRFLCDDNLLWKEKCRKAQILAEPRSDRPKRGRDGNMPPIASPWKAAY 969
            .||:.|:|.|.||..::||.|.:|.|||....|....|.|           .|: ...:.||...
 Frog   136 KYLDRKELGRCAQVSKAWRVLAEDELLWYRIGRSEGYLTE-----------SNL-TAGTSWKEVL 188

  Fly   970 MR----QHIIEMNWR-----SRPV-RKPKVLKGHDDHVITCL----QFSGNRIVSGSD--DNTLK 1018
            .:    :.::..||:     |.|. .:.|:::.:......|.    .|:......|.|  ..|..
 Frog   189 KQRRNNESMLRTNWKPHSADSLPADNRRKIIRLYTPISFQCACTRSHFTDEVQAHGEDFGTETRN 253

  Fly  1019 VWSAVN------GKCLRTLVGHTGGVWSSQMSGNIIISGSTDRTLKVWD-----MDSGACVHT-- 1070
            ...||:      ||.|..:..:.|          ::|:|.|...:::||     .|:.....|
 Frog   254 RTGAVSQLHYELGKVLCDVHSYDG----------VVIAGYTSGDVRLWDTRVSCFDAPYLKVTRD 308

  Fly  1071 ---LQGHTSTVRCMHLHGSKVVSGSRDATLRVWDIEQG----------------------SCLHV 1110
               |..|.| |..:.::.|..|:...|.|:.||.::.|                      :.:..
 Frog   309 PFDLTQHPS-VSFVKINRSLAVAVYEDGTVDVWSLQAGQEPIHHYQHNQKIQTLALCPESAAIAT 372

  Fly  1111 LVGHLAAVRCVQYDG-----------KLI-----VSG---------AYDYMVKIWHPERQE-CLH 1149
            ..|....|.|....|           ||:     :.|         |.:.||.:..||..| .||
 Frog   373 ASGFQIKVECPDERGYWRSTCHFQTQKLVNFLHLIHGSGGHPLAIAAAEEMVYLLRPEEPEKVLH 437

  Fly  1150 TLQGHTNRVYSLQFDGLHVVSG--------SLDTSIRVWDVETGNCKHTL---MGHQSLTSGMEL 1203
            :..||.  |..|.....|...|        :....|.|::::||.|..||   .|..|..:..:.
 Frog   438 STYGHP--VTCLDVSPTHAAFGVKSFGWFSNHGNKIHVYNLQTGQCLTTLGNSTGDFSCINLQDS 500

  Fly  1204 RQNILVSGNADSTVKVWDITTGQCLQTLSGPNKHHSAVTCLQFNSRFVVTSSDDGTVKLWDVKTG 1268
            ..|.||:||.|..|:|:|:   :|..:|.....||..|:.::.:...:|:...:|...:||.:.|
 Frog   501 PPNFLVTGNRDRRVRVYDM---RCSTSLCSFYGHHLGVSAVRMDDWKIVSGGVEGLTCVWDQRMG 562

  Fly  1269  1268
             Frog   563  562

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ago	NP_523922.1	F-box-like	892..938	CDD:289689	19/45 (42%)
		WD40	<981..1274	CDD:225201	81/370 (22%)
		WD40	988..1264	CDD:238121	76/356 (21%)
		WD40 repeat	998..1033	CDD:293791	10/46 (22%)
		WD40 repeat	1039..1073	CDD:293791	8/43 (19%)
		WD40 repeat	1078..1112	CDD:293791	8/55 (15%)
		WD40 repeat	1119..1152	CDD:293791	13/58 (22%)
		WD40 repeat	1158..1192	CDD:293791	11/44 (25%)
		WD40 repeat	1200..1232	CDD:293791	10/31 (32%)
		WD40 repeat	1241..1263	CDD:293791	3/21 (14%)
fbxw8	XP_017946093.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910