Protein Alignment pav and cmet

DIOPT Version :10

• Sequence 1: NP_477025.1
• Gene: pav / 38515
• FlyBaseID: FBgn0011692
• Length: 887
• Species: Drosophila melanogaster
• Sequence 2: NP_524993.3
• Gene: cmet / 53561
• FlyBaseID: FBgn0040232
• Length: 2189
• Species: Drosophila melanogaster
• Alignment Length: 820
• Identity: 199/820 - (24%)
• Similarity: 311/820 - (37%)
• Gaps: 282/820 - (34%)

  Fly    30 SDKARDPVNVFCRVRPLQSDADLTSL-RVKNSTTIALNPQDQLLQHHKPHNGAQREVQYIFKHVF 93
            |.|....:.|..:|||  .:..|||| :||...:|.|..     .|.:|         |:|.:||
  Fly     2 SAKNASSIQVCIKVRP--CEPGLTSLWQVKERRSIHLAD-----SHAEP---------YVFDYVF 50

  Fly    94 QPDATQQDVYAAVAQPLVENLLKGRNSLLFTYGVTGSGKTYTMTGNLRHRGIMPRCLDVLFRTIS 158
            ...|:.|:|:..:|:.:|...::|.|..:|.||.|.|||||||.|:.::.|:|......:|:.||
  Fly    51 DEGASNQEVFDRMAKHIVHACMQGFNGTIFAYGQTSSGKTYTMMGDEQNPGVMVLAAKEIFQQIS 115

  Fly   159 DYQAKKFVFKPDKLNGFEILSEEDALLERQHEMNQRFAGSGRFAFRHKDSDPEIASQASVEPIPL 223
            ..                  :|.|.||.
  Fly   116 SE------------------TERDFLLR------------------------------------- 125

  Fly   224 LGLDEDNMYSVFVTYIEIYNNSVYDLLEDSGIQKTLQSKIIREDANRHMFVHGVTEVE-----VK 283
                        |.||||||..:||||     .|..|...|.|..|      |:..|.     :.
  Fly   126 ------------VGYIEIYNEKIYDLL-----NKKNQDLKIHESGN------GIVNVNCEECIIT 167

  Fly   284 TVEDALEVFQMGQKRKRMGHTVLNAESSRSHSVFNIRLVQAPTD-SQGENVVQDRQNITVSQLSL 347
            :..|.|.:..:|.|.:.:|.|.:|..|||||::|.|.:....:| |..:.|:|       |.|:|
  Fly   168 SEVDLLRLLCLGNKERTVGETNMNERSSRSHAIFKIIIESRKSDHSDDDAVIQ-------SVLNL 225

  Fly   348 VDLAGSERSSRTKNTGVRLREAGNINNSLMTLRTCLEYLRENQLAASNGLAPKKVPYRDSKITHM 412
            ||||||||:.:|...|.||:|.|:||.||:.|...::.|.||   |.|    :...|||||:|.:
  Fly   226 VDLAGSERADQTGARGARLKEGGHINKSLLFLSNVIKSLSEN---ADN----RFTNYRDSKLTRI 283

  Fly   413 FKNYFDGEGQVSMIVCINPRIEDYDENMQVMKFAEMTQEVQI--------ARATPMKQ------- 462
            .:....|....|:|..|.|.|  .:|:...:.||...::::|        :.||.||:
  Fly   284 LQASLGGNAFTSIICTIKPSI--MEESQSTLSFATRAKKIRIKPQVNEMVSDATMMKRLEREIKV 346

  Fly   463 ---------------------------------------DLGLTPGRR----------------- 471
                                                   |.|....||
  Fly   347 LKDKLAEEERKNENQQKVEHLERQIKHDMHKIICGHSLSDKGQQKRRRTWCPTASGSHLELAETG 411

  Fly   472 ----------KANKLFKIAVNNLNELG-----IPEAKDL--EVDVGL-VYSLGPDF-PAYEMD-- 515
                      |.:.|.|....:.:..|     ||:..::  .:|:|. ..|:..:| ||..:|
  Fly   412 TTEDRIDQFPKVSHLPKPVFFHTSNAGKRWDNIPKTINILGSLDIGTESNSISEEFLPAECIDFG 476

  Fly   516 SP-----EAQIKIRELMH--------YLEQRIEKR-------KKLRANLDIKCDSFRQMLMNL-- 558
            ||     :..:.||:|..        ....:|:|.       ..|..:.:::|:..:.:...|
  Fly   477 SPRPDVLKPMLTIRQLPDLPLTPKGPLTTDKIKKEIQDLQMFTSLEKHFEVECEEVQGLKEKLAE 541

  Fly   559 ---DRDNLQLRTELASLKAVYKQERDRSAALEKKVRIHESSIDVLNNTLSKQERQIEEL--TFKL 618
               .||||: :..||        |::|..||||:|....:..:..|:.:|:.|.::..|  |.::
  Fly   542 VTAQRDNLE-QESLA--------EKERYDALEKEVTSLRADNEAANSKISELEEKLSTLKQTMRI 597

  Fly   619 NEKENML-TQKEHEKEKQKKKFSSKLAVESDKNKREFELKLREQRVKLQERMRIKDEKLRLVSNI 682
            .|.||.: ...|.|.|..||  ||||.|:.                              |:|.:
  Fly   598 MEVENQVAVGLEFEFEAHKK--SSKLRVDD------------------------------LLSAL 630

  Fly   683 LQSED-LPSLPRSQSS---ENILNEKDRGAYTARTEESSV 718
            |:.|. :.||.:|..:   :.:.|.|:....:...|:..:
  Fly   631 LEKESTIESLQKSLDNLTRDVLRNSKEGHMLSIAPEQEDI 670

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pav	NP_477025.1	KISc_KIF23_like	35..450	CDD:276819	124/421 (29%)
		PRK03918	<522..>687	CDD:235175	42/187 (22%)
		MKLP1_Arf_bdg	734..840	CDD:465166
cmet	NP_524993.3	Motor_domain	8..321	CDD:473979	124/422 (29%)
		SMC_prok_B	539..1431	CDD:274008	42/173 (24%)
		SMC_prok_B	1137..1926	CDD:274008
		YhaN	1717..2182	CDD:443752