Protein Alignment CG14997 and AIFM2

DIOPT Version :9

• Sequence 1: NP_647877.1
• Gene: CG14997 / 38514
• FlyBaseID: FBgn0035515
• Length: 457
• Species: Drosophila melanogaster
• Sequence 2: NP_001185625.1
• Gene: AIFM2 / 84883
• HGNCID: 21411
• Length: 373
• Species: Homo sapiens
• Alignment Length: 378
• Identity: 82/378 - (21%)
• Similarity: 137/378 - (36%)
• Gaps: 95/378 - (25%)

  Fly    35 SRVNRERQECQVLVVGGGTGGCAMAAKLSSRLGSDKVVVLEPEDKHYYQPMFTLIGGGMKRLDQS 99
            |:|:.|.....|::||||.||.|.|::|.:                 ....|.|:  .||  |..
Human     3 SQVSVESGALHVVIVGGGFGGIAAASQLQA-----------------LNVPFMLV--DMK--DSF 46

  Fly   100 HRQMADV-LPTKAKWVKEKALEF----------------DPDNNTVSTSGGKTIKYDFLIIATGL 147
            |..:|.: ...:..:.|:..:.:                |..|..|...||:.:.:..||:|||
Human    47 HHNVAALRASVETGFAKKTFISYSVTFKDNFRQGLVVGIDLKNQMVLLQGGEALPFSHLILATG- 110

  Fly   148 QLNYGKIPGLVEALETPDSNVCSIYSPKYVDHVYE-CLRRTNKGNAIFTFPNCPIKCAGAPQKIA 211
              :.|..||....:.:..:.:          ..|| .:|:..:...|.....   ..||. :..|
Human   111 --STGPFPGKFNEVSSQQAAI----------QAYEDMVRQVQRSRFIVVVGG---GSAGV-EMAA 159

  Fly   212 YISEHYFRKMGRRDNVNIIYNTSLPVIFGVKHYAEALMKLIKRRNITLNVQRNLVEVRHKDNIAV 276
            .|...|..|     .|.:|::   .|....|....::.:.:|...:...||..|.|     .::.
Human   160 EIKTEYPEK-----EVTLIHS---QVALADKELLPSVRQEVKEILLRKGVQLLLSE-----RVSN 211

  Fly   277 FEDLAKPGVHYEETYSMLHVTPPMSTPDVVANCKKLVT------------------PTGFVDVDQ 323
            .|:|  |...|.|   .:.|.....| :|..|...|.|                  .:|.:.|::
Human   212 LEEL--PLNEYRE---YIKVQTDKGT-EVATNLVILCTGIKINSSAYRKAFESRLASSGALRVNE 270

  Fly   324 LTLQHNKYSNVFAIGDSASSPNSKTAAAAAAQSPVVFKNVMAAIEGKAPTDIY 376
             .||...:|||:||||.|.....|.|..|...:.:...|::.::: :.|...|
Human   271 -HLQVEGHSNVYAIGDCADVRTPKMAYLAGLHANIAVANIVNSVK-QRPLQAY 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14997	NP_647877.1	Pyr_redox_2	59..342	CDD:285266	64/318 (20%)
AIFM2	NP_001185625.1	NirB	39..356	CDD:330997	68/325 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900