DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14997 and Sqor

DIOPT Version :9

Sequence 1:	NP_647877.1	Gene:	CG14997 / 38514	FlyBaseID:	FBgn0035515	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_001155975.1	Gene:	Sqor / 59010	MGIID:	1929899	Length:	450	Species:	Mus musculus

Alignment Length:	434	Identity:	213/434 - (49%)
Similarity:	289/434 - (66%)	Gaps:	8/434 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLLATHNHAPTAFSTRFLSTSRVNRERQECQVLVVGGGTGGCAMAAKLSSRLGSDKVVVLEPEDK 79
            |.|.|....|....|....|::.:.|     |||:|||.||..||.::..|:|::.|.::||.::
Mouse    20 LRLGTQQAGPLQLHTGACCTAKNHYE-----VLVLGGGAGGITMATRMKRRVGAENVAIVEPSER 79

  Fly    80 HYYQPMFTLIGGGMKRLDQSHRQMADVLPTKAKWVKEKALEFDPDNNTVSTSGGKTIKYDFLIIA 144
            |:|||::||:|.|.|.|..|.|....|:|:..:|::::..|.:||.|.:.|..||.|.|.:||||
Mouse    80 HFYQPIWTLVGAGAKELSLSVRSTLSVIPSGVQWIQDRVAELNPDENCIRTDSGKEISYRYLIIA 144

  Fly   145 TGLQLNYGKIPGLVEALETPDSNVCSIYSPKYVDHVYECLRRTNKGNAIFTFPNCPIKCAGAPQK 209
            .|:||:|.||.||.|....|  .:.|.||.|.|:..::.|:...:|||:|||||.|:||||||||
Mouse   145 LGIQLDYEKIKGLPEGFAYP--KIGSNYSVKTVEKTWKALQGFKEGNALFTFPNTPVKCAGAPQK 207

  Fly   210 IAYISEHYFRKMGRRDNVNIIYNTSLPVIFGVKHYAEALMKLIKRRNITLNVQRNLVEVRHKDNI 274
            |.|:||.||||.|:|...|||:||:|..|||||.||:||.::|:.|::::|.:.||:|||.....
Mouse   208 IMYLSEAYFRKTGKRPKANIIFNTALGTIFGVKKYADALQEIIRERDVSVNYKHNLIEVRPDKQE 272

  Fly   275 AVFEDLAKPGVHYEETYSMLHVTPPMSTPDVVANCKKLVTPTGFVDVDQLTLQHNKYSNVFAIGD 339
            ||||.|.|||..:...|.|||||||||.|||:.. ..:....|:||||:.||||.||.|||.|||
Mouse   273 AVFEILDKPGETHVIPYEMLHVTPPMSAPDVLKR-SPVADSAGWVDVDKETLQHKKYPNVFGIGD 336

  Fly   340 SASSPNSKTAAAAAAQSPVVFKNVMAAIEGKAPTDIYDGYSSCPIVTGYSSCILAEFDYNLTPVE 404
            ..:.|.||||||.||||.::.:.:...::.:.|...||||:|||:||||:..|||||||...|:|
Mouse   337 CTNLPTSKTAAAVAAQSGILDRTMCLIMKNQRPIKKYDGYTSCPLVTGYNRVILAEFDYTAQPLE 401

  Fly   405 TFPLDQSKERYSMFFMKKELMPVLYWKLMMNGYWNGPALMRKIF 448
            |||.||||||.:|:.||.::||.|||.:|:.|||.|||.:||:|
Mouse   402 TFPFDQSKERITMYLMKADMMPFLYWNMMLRGYWGGPAFLRKLF 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14997	NP_647877.1	Pyr_redox_2	59..342	CDD:285266	138/282 (49%)
Sqor	NP_001155975.1	FadH2	46..397	CDD:223523	177/353 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167849317
Domainoid	1	1.000	202	1.000	Domainoid score	I2986
eggNOG	1	0.900	-	-		E1_COG0446
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10921
Inparanoid	1	1.050	434	1.000	Inparanoid score	I1688
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62271
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005877
OrthoInspector	1	1.000	-	-		oto93028
orthoMCL	1	0.900	-	-		OOG6_102907
Panther	1	1.100	-	-	LDO	PTHR10632
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R564
SonicParanoid	1	1.000	-	-		X4272
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790