DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14997 and CG10700

DIOPT Version :9

Sequence 1:	NP_647877.1	Gene:	CG14997 / 38514	FlyBaseID:	FBgn0035515	Length:	457	Species:	Drosophila melanogaster
Sequence 2:	NP_609942.1	Gene:	CG10700 / 35183	FlyBaseID:	FBgn0032754	Length:	539	Species:	Drosophila melanogaster

Alignment Length:	334	Identity:	70/334 - (20%)
Similarity:	124/334 - (37%)	Gaps:	95/334 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 LVVGGGTGGCAMAAKLSSRLGSDKVVVLEPEDKHYYQPMFTLIGGGMKRLDQSHRQMADVLPTKA 111
            :|||||..|               .|.:|...:..:....||: .|.|.|.....::.::|.|..
  Fly   135 VVVGGGPSG---------------AVCVETLRQEGFTGRLTLV-CGEKHLPYDRTRIMNLLNTYT 183

  Fly   112 K--------WVKEKALE---------FDPDNNTVSTSGGKTIKYDFLIIATGLQLNYGKIPGLVE 159
            |        :.|:..:|         .|.:.||:..:.|||..||.:.||||.......|||:
  Fly   184 KNLALREEQFYKDYGIEMQLGVSAERLDTNCNTLHCTNGKTFPYDKIYIATGYSAVTPNIPGV-- 246

  Fly   160 ALETPDSNVCSIYSPKYVDHVYECLRRTNKGNAIFTF--PNCPIKCAGAPQKIAYIS-EHYFRKM 221
                            ::.:| :.:|......:||..  .:..:.|.|:    :::: |.....:
  Fly   247 ----------------HLKNV-KVIRNIGDARSIFKMVDKSTQVVCLGS----SFMAVEATANLV 290

  Fly   222 GRRDNV------NIIYNTSLPVIFGVKHYAEALMKLIKRRNITL-----------NVQRNLVEVR 269
            .|..:|      |:.:.::|..:.|     :.::||::...:.|           |.:..:|.|:
  Fly   291 SRARSVTLVARQNVPFKSTLGELIG-----QRILKLLEENKVDLRMSSGIIRILGNSRGEVVAVK 350

  Fly   270 HKDNIAVFEDLAKPGVHYEETYSMLHVTPPMSTPDVVANCKKLVTPTGFVDVDQLTLQHNKYSNV 334
            ..||..:..:|...|            |......|.:......:.|.|.|||:.. || .|..||
  Fly   351 LLDNSRIPCNLLILG------------TGCQCNTDFLQRSGININPNGSVDVNDF-LQ-TKVRNV 401

  Fly   335 FAIGDSASS 343
            :..||.|::
  Fly   402 YVGGDIANA 410

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14997	NP_647877.1	Pyr_redox_2	59..342	CDD:285266	63/319 (20%)
CG10700	NP_609942.1	Rieske_AIFL_N	10..106	CDD:239560
		Pyr_redox_2	135..414	CDD:285266	70/334 (21%)
		Pyr_redox	273..350	CDD:278498	13/85 (15%)
		COG3393	336..>508	CDD:225928	22/89 (25%)
		Reductase_C	464..527	CDD:291425
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0446
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.810