DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment ImpL2 and Igsf9

DIOPT Version :9

Sequence 1:NP_728961.2 Gene:ImpL2 / 38513 FlyBaseID:FBgn0001257 Length:267 Species:Drosophila melanogaster
Sequence 2:NP_001139272.1 Gene:Igsf9 / 93842 MGIID:2135283 Length:1179 Species:Mus musculus


Alignment Length:241 Identity:47/241 - (19%)
Similarity:85/241 - (35%) Gaps:67/241 - (27%)


- Green bases have known domain annotations that are detailed below.


  Fly    44 EEEKPRNRAFEADWL--------KFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRS 100
            ::..|........|:        :|.:|||..|:..:...:.:.|...||..|.:.|      :.
Mouse   114 DQHSPEQDFANGSWVHLTVNSPPQFQETPPLVLEVKELEAVTLRCVARGSPQPYVTW------KF 172

  Fly   101 ELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYAST---------VVHP 156
            ...||...|...:..:..:.:|...     ...|..|||...:...:|..:|         :|.|
Mouse   173 RGQDLGKGQGQVQVQNGTLWIRRVE-----RGSAGDYTCQASSSEGSITHATQLLVLGPPVIVVP 232

  Fly   157 PRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITW------LNNENKEI 215
            |.:|.:...:                       ::.|.||..|.| |.:|:      :|..:...
Mouse   233 PSNSTVNSSQ-----------------------DVSLACRAEAYP-ANLTYSWFQDGVNVFHISR 273

  Fly   216 VQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFVYP 261
            :|. |.|:|.:|.|.:...:.:|.|:|.|:..|        .|::|
Mouse   274 LQS-RVRILVDGSLWLQATQPDDAGHYTCVPSN--------GFLHP 310

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ImpL2NP_728961.2 IGc2 187..251 CDD:197706 19/69 (28%)
Igsf9NP_001139272.1 IG_like 28..110 CDD:214653
Ig 136..223 CDD:386229 20/97 (21%)
Ig_3 227..305 CDD:372822 22/102 (22%)
Ig 341..404 CDD:386229
Ig 436..500 CDD:319273
FN3 508..599 CDD:238020
FN3 625..715 CDD:238020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 767..807
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 819..842
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 942..974
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1016..1079
PDZ-binding 1177..1179
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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