DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpL2 and prtgb

DIOPT Version :9

Sequence 1:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	XP_005174269.3	Gene:	prtgb / 572241	ZFINID:	ZDB-GENE-060302-1	Length:	1150	Species:	Danio rerio

Alignment Length:	210	Identity:	46/210 - (21%)
Similarity:	76/210 - (36%)	Gaps:	43/210 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 PTKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELD----DLDSNQVAEEAPSAIVRVRSSH 125
            |..:..|....:.:.|...|:..|.:.|       |..|    |:.:..|.......|..|::.|
Zfish   227 PQNISVALHQPVVLECLAEGNPRPLVSW-------SRADSKPIDVSAASVLGNGNLMISAVKAHH 284

  Fly   126 IIDHVLSEARTYTCVGRTGSKTIYAS-----TVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLD 185
                    :.||.|...|.....|.:     ||:.||........:|.|.|...|
Zfish   285 --------SGTYVCRATTPGTRNYTTAAGNVTVLLPPSLVEKPESQTRPRAGTAR---------- 331

  Fly   186 LMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVV 250
                   ..|:....|..:|||.  :|.|:::.:....:.|..|:|::|..||...|:|:|.|..
Zfish   332 -------FSCQAEGTPTPQITWF--KNGEVIRTNGRTKMYNNKLVITQIIPEDDAFYQCLAENSQ 387

  Fly   251 GKDTADTFVYPVLNE 265
            |...:.:.:..|.:|
Zfish   388 GSVVSTSRLIVVQSE 402

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	17/63 (27%)
prtgb	XP_005174269.3	Ig	31..118	CDD:325142
		I-set	123..207	CDD:333254
		Ig_3	220..293	CDD:316449	16/80 (20%)
		I-set	313..398	CDD:254352	23/103 (22%)
		FN3	405..498	CDD:238020
		FN3	509..599	CDD:238020
		FN3	608..687	CDD:238020
		FN3	711..802	CDD:238020
		FN3	809..899	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910