DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpL2 and paplna

DIOPT Version :9

Sequence 1:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	XP_005169942.1	Gene:	paplna / 562930	ZFINID:	ZDB-GENE-070815-4	Length:	1187	Species:	Danio rerio

Alignment Length:	204	Identity:	48/204 - (23%)
Similarity:	83/204 - (40%)	Gaps:	29/204 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 PPTKLQQADGATIEIVCEMMGSQVPSIQWVVG-HLPRSELDDL---------DSNQVAEEAPSAI 118
            ||:..|::      :.|::..:..|..||... :..||....|         :||..|.|.....
Zfish   710 PPSNTQRS------LSCDLPNTVGPCDQWTSRFYFDRSASRCLHFWYGGCHGNSNNFASEEECQK 768

  Fly   119 VRVRS---SHIIDHVLS---EARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPG----AQK 173
            :.:||   .....||||   ..|.:....:..|...:.:...|.|.|:.:  :::.|.    |:.
Zfish   769 MCLRSELRQRDQAHVLSLQHGRRRFPAHVQLSSSGAHRAQRAHQPASNAM--QQSNPAASWTAEG 831

  Fly   174 PRIIYTEKTHLD-LMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLANGDLLISEIKWE 237
            ..|..|:.:.:: |:|..:.|||||...|.:.:......:...|...||....:|.||:..|..:
Zfish   832 VSIDKTDPSTVEGLVGQRVVLPCRVTPPPSSAVLVEWRRDGVPVDPTRHEQQLDGSLLVGPITLQ 896

  Fly   238 DMGNYKCIA 246
            |.|.:.|:|
Zfish   897 DSGWFLCVA 905

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	18/60 (30%)
paplna	XP_005169942.1	TSP1	24..75	CDD:214559
		ADAM_spacer1	181..293	CDD:310520
		TSP1	303..356	CDD:214559
		TSP1	388..442	CDD:214559
		TSP1	449..498	CDD:214559
		TSP1	504..557	CDD:214559
		KU	720..771	CDD:238057	11/50 (22%)
		Ig_3	839..906	CDD:316449	19/67 (28%)
		IGc2	960..1022	CDD:197706
		I-set	1039..1121	CDD:333254
		PLAC	1142..1173	CDD:312271
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900