DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpL2 and opcml

DIOPT Version :9

Sequence 1:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_001005580.1	Gene:	opcml / 449538	ZFINID:	ZDB-GENE-040927-3	Length:	342	Species:	Danio rerio

Alignment Length:	205	Identity:	46/205 - (22%)
Similarity:	74/205 - (36%)	Gaps:	46/205 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    66 TKLQQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHV 130
            |.:...:|:.:.::|..:|...|||.|                           :.|||. .:.:
Zfish   140 TDVSVNEGSNVSLMCLAIGRPEPSILW---------------------------KFRSSK-GNRI 176

  Fly   131 LSEARTYTCVGRT----GSKTIYASTVVHPP--RSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGS 189
            ::|.......|.|    ||.....|..:.||  |:.::|       ...|.:|...::....:|.
Zfish   177 VTEGEYVEMTGITKDMSGSYDCITSNDISPPDVRTVQVT-------VNYPPVISRARSTGTAVGQ 234

  Fly   190 NIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVLAN----GDLLISEIKWEDMGNYKCIARNVV 250
            ...|.|...|.|.|:..|...| :.|:.|.....:.|    ..|....:..||.|||.|:|.|.:
Zfish   235 KGVLWCEASAVPLADFQWFKGE-RRILNGFNGVKIENKGKQSMLTFFNVSEEDYGNYTCVAINTL 298

  Fly   251 GKDTADTFVY 260
            |...|...:|
Zfish   299 GITNASIILY 308

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	20/67 (30%)
opcml	NP_001005580.1	Ig	41..129	CDD:299845
		IG_like	41..129	CDD:214653
		IG_like	139..216	CDD:214653	21/110 (19%)
		IGc2	146..202	CDD:197706	15/83 (18%)
		I-set	219..307	CDD:254352	24/88 (27%)
		ig	223..307	CDD:278476	22/84 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900