DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpL2 and klg

DIOPT Version :9

Sequence 1:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_524454.2	Gene:	klg / 42707	FlyBaseID:	FBgn0017590	Length:	545	Species:	Drosophila melanogaster

Alignment Length:	277	Identity:	65/277 - (23%)
Similarity:	101/277 - (36%)	Gaps:	86/277 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLLFGSIATVRGRAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWL-----KFTK---------TP 64
            :|...:|...|...|.|:|..|     :|..:.:|::   ..|::     |..:         .|
  Fly   140 VLTASNIMVTRDERVRLIDGYN-----LEISDLEPQD---AGDYVCQISDKINRDQVHTVEILVP 196

  Fly    65 PT--------KLQQADGATIEIVCEMMGSQVPSIQWV-----------VGHLPRSELDDLDSNQV 110
            |:        :||...|..|.:.|:..|:.||||.|.           :|..|...|:.|:..|
  Fly   197 PSVRAIPTSGQLQARKGGPITLECKGSGNPVPSIYWTKKSGANKSTARIGDGPILTLEKLERQQ- 260

  Fly   111 AEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPR 175
                                   |..|.|....|         |..|.:..:..:..||..
  Fly   261 -----------------------AGVYQCTADNG---------VGDPVTVDMRLDVLYPPD---- 289

  Fly   176 IIYTEKTHLDL-MGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHRVL---ANGDLL-ISEIK 235
             |..||:.:.. .|...:|.|.|.|.|.|.::|.  :|...:|....|::   ||..:| |..|:
  Fly   290 -IQVEKSWIHSGEGFEAKLVCIVFADPVATVSWY--QNSFPIQSTDRRIMATRANRHMLTIRHIQ 351

  Fly   236 WEDMGNYKCIARNVVGK 252
            .||.|||.|:|.|.:|:
  Fly   352 QEDFGNYSCVADNSLGR 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	24/67 (36%)
klg	NP_524454.2	DUF1370	63..>124	CDD:284518
		IG_like	109..195	CDD:214653	11/62 (18%)
		Ig	118..191	CDD:143165	11/58 (19%)
		IG_like	205..274	CDD:214653	21/101 (21%)
		IGc2	213..273	CDD:197706	18/92 (20%)
		IGc2	301..367	CDD:197706	24/67 (36%)
		FN3	392..486	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900