DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpL2 and CG13506

DIOPT Version :9

Sequence 1:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_001286718.1	Gene:	CG13506 / 37556	FlyBaseID:	FBgn0034723	Length:	503	Species:	Drosophila melanogaster

Alignment Length:	247	Identity:	46/247 - (18%)
Similarity:	86/247 - (34%)	Gaps:	70/247 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 GRAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPS 89
            |..:.::.|..|:.:         |::.|               :|.|...:|  |........:
  Fly   161 GARLSILCDDRDITD---------RSQTF---------------RQGDHHKLE--CRTYLPDNAT 199

  Fly    90 IQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHV-LSEARTYTCVGRTGSKTIYASTV 153
            |:|        ..:||:..      ||::.......|:|:| ...|..|.|:...||:
  Fly   200 IKW--------SFNDLNGQ------PSSVDNQNGVIILDNVDEKNAGDYQCLADDGSR------- 243

  Fly   154 VHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDL-MGSNIQLPCRVHARPRAEITWLNNEN----- 212
             |||..:      .:...|...|:.|.:.:::. .|:..:|.|...|:|.....::.:..
  Fly   244 -HPPHGT------VHIDVQYSPIVSTHRHNVNTEKGATAELYCNYRAKPIGRSYFIKDGKTLQLS 301

  Fly   213 -----KEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADTFV 259
                 |:.|....:|.    .|::.|:...|:|.|.|...|.:|.:.....|
  Fly   302 DKYSLKDSVHNDHNRT----TLIVREVTDSDLGEYLCQVENAIGSNEVKVHV 349

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	15/73 (21%)
CG13506	NP_001286718.1	IG_like	79..146	CDD:214653
		IGc2	83..146	CDD:197706
		IG_like	176..254	CDD:214653	23/122 (19%)
		Ig	176..239	CDD:299845	18/93 (19%)
		I-set	258..349	CDD:254352	18/94 (19%)
		Ig	275..348	CDD:143165	15/76 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900