DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpL2 and wrapper

DIOPT Version :9

Sequence 1:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_477404.1	Gene:	wrapper / 37555	FlyBaseID:	FBgn0025878	Length:	500	Species:	Drosophila melanogaster

Alignment Length:	353	Identity:	65/353 - (18%)
Similarity:	114/353 - (32%)	Gaps:	147/353 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 MNLHVCALALLLFGSIATVRGRAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKT------ 63
            |..|:|::...|..  |.:.|:....:|.:||::||.:.:......:.:|.|.::...|
  Fly     1 MTPHMCSVVRCLLA--ALILGQVQAELDFNNDLENSQKFKSIPTTVKTYENDTVQLPCTLNTPFR 63

  Fly    64 --------------------PPTKL---------------------------------------- 68
                                ||.::
  Fly    64 YVRWHRDDVALVDSRHPELPPPDRIMLWPNGSLQVANVQSSDTGDYYCEMNSDSGHVVQQHAIEV 128

  Fly    69 --------------QQADGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEA----- 114
                          :|..||..|:|||..|...|.|.|           .|:.|.:..::
  Fly   129 QLAPQVLIEPSDLTEQRIGAIFEVVCEAQGVPQPVITW-----------RLNGNVIQPQSNTGNR 182

  Fly   115 PSAIVRVRSSHIIDHVLSEARTYTCVGRTG-SKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIY 178
            .|.|:.::|.       ::|....||...| .:...|:..:|    ...:||.:.|   :| ::|
  Fly   183 QSLILEIKSR-------NQAGLIECVASNGVGEPAVANVYLH----VLFSPEVSIP---QP-VVY 232

  Fly   179 TEKTHLDLMGSNIQLPCRVHARPRAEITWLNN------------------ENKEI---VQGHRHR 222
            |:      :||...|.|.|.|.|.|.:.|.::                  .|:.:   |...||.
  Fly   233 TK------LGSRAHLECIVEAAPAATVKWFHHGLPVALGAHSTTHESELQTNRSVDHYVNAVRHM 291

  Fly   223 VLANGDLLISEIKWEDMGNYKCIARNVV 250
                  |::..::..|||.|:|.|.|.:
  Fly   292 ------LVVKSVRNADMGQYECRASNQI 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	21/85 (25%)
wrapper	NP_477404.1	Ig	41..124	CDD:299845	5/82 (6%)
		IG_like	41..118	CDD:214653	5/76 (7%)
		IG_like	145..218	CDD:214653	21/94 (22%)
		Ig	147..219	CDD:299845	21/93 (23%)
		I-set	224..323	CDD:254352	25/106 (24%)
		IGc2	236..314	CDD:197706	21/84 (25%)
		FN3	339..431	CDD:238020
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900