Protein Alignment ImpL2 and Dscam1

DIOPT Version :10

• Sequence 1: NP_728961.2
• Gene: ImpL2 / 38513
• FlyBaseID: FBgn0001257
• Length: 267
• Species: Drosophila melanogaster
• Sequence 2: NP_001246162.1
• Gene: Dscam1 / 35652
• FlyBaseID: FBgn0033159
• Length: 2038
• Species: Drosophila melanogaster
• Alignment Length: 365
• Identity: 65/365 - (17%)
• Similarity: 107/365 - (29%)
• Gaps: 157/365 - (43%)

  Fly    14 LLLFGSIATVRGRAVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEI 78
            |:||.::|.:...:..|      ..|..:|:::.|          .|.|.|..::..::....||
  Fly    11 LMLFAAVALIACGSQTL------AANPPDADQKGP----------VFLKEPTNRIDFSNSTGAEI 59

  Fly    79 VCEMMGSQVPSIQWV------VGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTY 137
            .|:..|:.:|.|.|:      ||.:|       ...|::.:........|:......|  .|:.|
  Fly    60 ECKASGNPMPEIIWIRSDGTAVGDVP-------GLRQISSDGKLVFPPFRAEDYRQEV--HAQVY 115

  Fly   138 TCVGRTG-----SKTIYASTVV--------------------------------------HPPRS 159
            .|:.|..     |:.::...||                                      |....
  Fly   116 ACLARNQFGSIISRDVHVRAVVSQHYEEDIHKAFVIRGNSAILKCDIPSFVADFVNVISWHSDEK 180

  Fly   160 SRLTPEKTYPG---------------------------------------AQKPRIIYTE----- 180
            ....|...|.|                                       |.|.|::.||
  Fly   181 ENFYPGTEYDGKYLVLPSGELHIREVGPEDGYKSYQCRTKHRLTGETRLSATKGRLVITEPVGSV 245

  Fly   181 ---------KTHLDL-----MGSNIQLPCRVHARPRAEITW--------------LNNENKEIVQ 217
                     :.|:.|     ||| :.|.|...|.|.....|              ||:..|::
  Fly   246 SPQLSGNGNQEHITLTRVPKMGS-VTLMCPAQAYPVPFFRWYKFIEGTTRKQAVVLNDRVKQV-- 307

  Fly   218 GHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDTADT 257
                    :|.|:|.:...||.|.|.|:..|.||.::.:|
  Fly   308 --------SGTLIIKDAVVEDSGKYLCVVNNSVGGESVET 339

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ImpL2	NP_728961.2	PHA02785	<74..246	CDD:165149	50/292 (17%)
		Ig_3	173..248	CDD:464046	25/107 (23%)
Dscam1	NP_001246162.1	IgI_1_Dscam	38..136	CDD:409547	22/116 (19%)
		Ig strand A	39..42	CDD:409547	1/12 (8%)
		Ig strand A'	48..52	CDD:409547	0/3 (0%)
		Ig strand B	55..64	CDD:409547	3/8 (38%)
		Ig strand C	70..76	CDD:409547	2/5 (40%)
		Ig strand C'	78..81	CDD:409547	0/2 (0%)
		Ig strand D	87..90	CDD:409547	0/2 (0%)
		Ig strand E	95..100	CDD:409547	0/4 (0%)
		Ig strand F	113..121	CDD:409547	2/7 (29%)
		Ig strand G	124..136	CDD:409547	1/11 (9%)
		IgI_2_Dscam	246..343	CDD:409545	25/105 (24%)
		Ig strand A	247..250	CDD:409545	0/2 (0%)
		Ig strand A'	260..264	CDD:409545	1/3 (33%)
		Ig strand B	267..274	CDD:409545	3/7 (43%)
		Ig strand C	282..288	CDD:409545	1/5 (20%)
		Ig strand C'	294..297	CDD:409545	0/2 (0%)
		Ig strand D	303..307	CDD:409545	1/3 (33%)
		Ig strand E	309..315	CDD:409545	3/5 (60%)
		Ig strand F	322..330	CDD:409545	3/7 (43%)
		Ig strand G	333..343	CDD:409545	2/7 (29%)
		IgC2_3_Dscam	346..426	CDD:409549
		Ig strand A	347..352	CDD:409549
		Ig strand A'	355..359	CDD:409549
		Ig strand B	362..372	CDD:409549
		Ig strand C	377..383	CDD:409549
		Ig strand C'	384..387	CDD:409549
		Ig strand E	392..398	CDD:409549
		Ig strand F	405..413	CDD:409549
		Ig strand G	416..426	CDD:409549
		IgI_4_Dscam	432..527	CDD:409548
		Ig strand A	432..435	CDD:409548
		Ig strand A'	441..445	CDD:409548
		Ig strand B	448..457	CDD:409548
		Ig strand C	462..468	CDD:409548
		Ig strand C'	470..473	CDD:409548
		Ig strand D	478..486	CDD:409548
		Ig strand E	490..499	CDD:409548
		Ig strand F	506..514	CDD:409548
		Ig strand G	517..527	CDD:409548
		IgI_5_Dscam	531..618	CDD:409550
		Ig strand A	531..533	CDD:409550
		Ig strand A'	538..542	CDD:409550
		Ig strand B	545..552	CDD:409550
		Ig strand C	559..565	CDD:409550
		Ig strand C'	566..568	CDD:409550
		Ig strand D	575..579	CDD:409550
		Ig strand E	582..588	CDD:409550
		Ig strand F	596..604	CDD:409550
		Ig strand G	608..618	CDD:409550
		Ig	621..718	CDD:472250
		Ig strand B	639..643	CDD:409353
		Ig strand C	653..657	CDD:409353
		Ig strand E	684..688	CDD:409353
		Ig strand F	698..703	CDD:409353
		Ig strand G	711..714	CDD:409353
		IgI_7_Dscam	721..815	CDD:409546
		Ig strand A	721..725	CDD:409546
		Ig strand A'	730..734	CDD:409546
		Ig strand B	737..746	CDD:409546
		Ig strand C	752..758	CDD:409546
		Ig strand C'	764..767	CDD:409546
		Ig strand D	775..778	CDD:409546
		Ig strand E	780..786	CDD:409546
		Ig strand F	793..801	CDD:409546
Ig strand G	806..815	CDD:409546
Ig	818..916	CDD:472250
Ig strand B	836..840	CDD:409353
Ig strand C	849..853	CDD:409353
Ig strand E	880..884	CDD:409353
Ig strand F	894..899	CDD:409353
FN3	<899..1212	CDD:442628
Ig strand G	907..910	CDD:409353
FN3	1222..1312	CDD:238020
Ig	<1339..1406	CDD:472250
Ig strand C	1350..1354	CDD:409358
Ig strand E	1372..1376	CDD:409358
Ig strand F	1386..1391	CDD:409358
Ig strand G	1399..1402	CDD:409358
FN3	1409..1499	CDD:238020
FN3	1504..1584	CDD:238020
Dscam_C	1893..2008	CDD:463546