DRSC/TRiP Functional Genomics Resources

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Protein Alignment ImpL2 and LRIT3

DIOPT Version :9

Sequence 1:NP_728961.2 Gene:ImpL2 / 38513 FlyBaseID:FBgn0001257 Length:267 Species:Drosophila melanogaster
Sequence 2:NP_940908.3 Gene:LRIT3 / 345193 HGNCID:24783 Length:679 Species:Homo sapiens


Alignment Length:200 Identity:46/200 - (23%)
Similarity:76/200 - (38%) Gaps:67/200 - (33%)


- Green bases have known domain annotations that are detailed below.


  Fly   104 DLDSNQVAE-------------EAPSAIVRVRSSHII-----------DHVLSEARTYTCVGRTG 144
            ||.||::..             ..||.::.:..|.||           .|:              
Human   159 DLSSNRLTTLPPDFLESWTHLVSTPSGVLDLSPSRIILGLQDNPWFCDCHI-------------- 209

  Fly   145 SKTIYASTVVHP------PRSSRLTPEK----TYPGAQ-----KPRIIYTEKTHLDLMGSNIQLP 194
            ||.|..|.||.|      |..:...||:    .:..|:     ||.::.:....:..:|||:.|.
Human   210 SKMIELSKVVDPAIVLLDPLMTCSEPERLTGILFQRAELEHCLKPSVMTSATKIMSALGSNVLLR 274

  Fly   195 CRVHARPRAEITWLNNE----NKEIVQ-----GHRHRVLANGDLLISEIKWEDMGNYKCIARNVV 250
            |.....|..:|||..::    |..::|     |.|..:::     ::.|..:|.|:|||.|:|:.
Human   275 CDATGFPTPQITWTRSDSSPVNYTVIQESPEEGVRWSIMS-----LTGISSKDAGDYKCKAKNLA 334

  Fly   251 GKDTA 255
            |...|
Human   335 GMSEA 339

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ImpL2NP_728961.2 IGc2 187..251 CDD:197706 21/72 (29%)
LRIT3NP_940908.3 LRR 1 56..79
leucine-rich repeat 59..82 CDD:275378
LRR_8 61..117 CDD:290566
LRR 2 80..103
leucine-rich repeat 83..106 CDD:275378
LRR 3 104..128
LRR_8 105..165 CDD:290566 4/5 (80%)
LRR_4 105..146 CDD:289563
leucine-rich repeat 107..130 CDD:275378
LRR 4 129..151
LRR_4 131..170 CDD:289563 4/10 (40%)
leucine-rich repeat 131..154 CDD:275378
LRR 5 152..175 4/15 (27%)
leucine-rich repeat 155..168 CDD:275378 4/8 (50%)
Ig 267..345 CDD:299845 22/77 (29%)
IG_like 267..345 CDD:214653 22/77 (29%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 351..375
FN3 486..550 CDD:214495
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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