DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpL2 and itgb4

DIOPT Version :9

Sequence 1:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	XP_005166847.1	Gene:	itgb4 / 335269	ZFINID:	ZDB-GENE-030131-7209	Length:	1931	Species:	Danio rerio

Alignment Length:	101	Identity:	21/101 - (20%)
Similarity:	43/101 - (42%)	Gaps:	26/101 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 VGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTC--------VGRTGSKTIYA 150
            :|..||:.:      .:|::..|:::..:.|         .:|::.        |.|||::...|
Zfish  1093 LGRYPRTVI------TIADKPESSVMAFKKS---------TQTFSTTDSLYTIPVERTGNRETPA 1142

  Fly   151 STVVHPPRSSRL---TPEKTYPGAQKPRIIYTEKTH 183
            :......::||.   :|.|..||..:..|:...:||
Zfish  1143 TVHWRTNKASRFDISSPLKFAPGEAEKNILINPRTH 1178

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706
itgb4	XP_005166847.1	Integrin_beta	37..457	CDD:278776
		EGF_2	<468..490	CDD:285248
		EGF_2	545..573	CDD:285248
		Integrin_B_tail	625..709	CDD:285239
		Calx-beta	991..1064	CDD:295344
		FN3	1242..1326	CDD:238020
		FN3	1331..1420	CDD:238020
		fn3	1640..1720	CDD:278470
		fn3	1751..1835	CDD:278470
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900