DRSC/TRiP Functional Genomics Resources

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Protein Alignment ImpL2 and Negr1

DIOPT Version :9

Sequence 1:NP_728961.2 Gene:ImpL2 / 38513 FlyBaseID:FBgn0001257 Length:267 Species:Drosophila melanogaster
Sequence 2:XP_036019026.1 Gene:Negr1 / 320840 MGIID:2444846 Length:362 Species:Mus musculus


Alignment Length:264 Identity:50/264 - (18%)
Similarity:85/264 - (32%) Gaps:74/264 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly    19 SIATVRGR-------AVDLVDDSNDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQA----- 71
            ||:|:..|       .||:.|| .....|::. :..||...     :..|...|.|:...     
Mouse    86 SISTLNKRDYSLQIQNVDVTDD-GPYTCSVQT-QHTPRTMQ-----VHLTVQVPPKIYDISNDMT 143

  Fly    72 --DGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLS-- 132
              :|..:.:.|...|...|.|.|  .|:                :|||.......::..:.::  
Mouse   144 INEGTNVTLTCLATGKPEPVISW--RHI----------------SPSAKPFENGQYLDIYGITRD 190

  Fly   133 EARTYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLP--- 194
            :|..|.|....                     :.::|..:|.|:|......:..:.|....|   
Mouse   191 QAGEYECSAEN---------------------DVSFPDVKKVRVIVNFAPTIQEIKSGTVTPGRS 234

  Fly   195 ----CRVHARPRAEITWLNNENKEIVQGHRHRVLAN----GDLLISEIKWEDMGNYKCIARNVVG 251
                |.....|.....|...| |.:..|.:..::.|    ..|.::.:..|..|||.|:|.|.:|
Mouse   235 GLIRCEGAGVPPPAFEWYKGE-KRLFNGQQGIIIQNFSTRSILTVTNVTQEHFGNYTCVAANKLG 298

  Fly   252 KDTA 255
            ...|
Mouse   299 TTNA 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ImpL2NP_728961.2 IGc2 187..251 CDD:197706 17/74 (23%)
Negr1XP_036019026.1 FR1 38..55 CDD:409353
Ig strand A' 40..46 CDD:409353
IG_like 41..129 CDD:214653 11/49 (22%)
Ig strand B 48..56 CDD:409353
CDR1 56..60 CDD:409353
FR2 61..68 CDD:409353
Ig strand C 61..67 CDD:409353
CDR2 69..79 CDD:409353
Ig strand C' 71..74 CDD:409353
Ig strand C' 76..79 CDD:409353
FR3 80..115 CDD:409353 9/29 (31%)
Ig strand D 84..91 CDD:409353 3/4 (75%)
Ig strand E 94..100 CDD:409353 0/5 (0%)
Ig strand F 107..115 CDD:409353 2/8 (25%)
CDR3 116..120 CDD:409353 0/4 (0%)
Ig strand G 120..129 CDD:409353 2/13 (15%)
FR4 122..129 CDD:409353 0/11 (0%)
Ig strand A' 139..144 CDD:409353 0/4 (0%)
IGc2 146..204 CDD:197706 13/96 (14%)
Ig strand B 150..157 CDD:409353 1/6 (17%)
Ig strand C 163..168 CDD:409353 2/6 (33%)
Ig strand C' 170..172 CDD:409353 0/1 (0%)
Ig strand E 180..186 CDD:409353 0/5 (0%)
Ig strand F 193..200 CDD:409353 2/6 (33%)
Ig_3 219..295 CDD:404760 16/76 (21%)
putative Ig strand A 219..225 CDD:409353 0/5 (0%)
Ig strand B 235..239 CDD:409353 0/3 (0%)
Ig strand C 248..252 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 3/4 (75%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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