DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpL2 and Igsf9b

DIOPT Version :9

Sequence 1:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_001363879.1	Gene:	Igsf9b / 315510	RGDID:	1564717	Length:	1441	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	59/218 - (27%)
Similarity:	87/218 - (39%)	Gaps:	42/218 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    60 FTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWV-VGHLPRSELDDLDSNQVAEEAPSAIVRVRS 123
            ||:|||..::..:|.:|.:.|...|:..|.:.|: .|.|    |......||::          .
  Rat   141 FTETPPQYIEAKEGGSITMTCTAFGNPKPIVTWLKEGTL----LSASGKYQVSD----------G 191

  Fly   124 SHIIDHVLSEAR-TYTCVGRTGSKTIYASTVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDL- 186
            |..:..|..|.| .|||  |..|   .....||          .|:...|.|..|.:...::.:
  Rat   192 SLTVTSVSREDRGAYTC--RAYS---IQGEAVH----------TTHLLVQGPPFIVSPPENITVN 241

  Fly   187 MGSNIQLPCRVHARP-RAEITWLNNENKEIVQGH---RHRVLANGDLLISEIKWEDMGNYKCIAR 247
            :..:..|.||..|.| ....||...:.....|..   |.|:|.:|.|:|..:|.||.|.|.|:..
  Rat   242 ISQDALLTCRAEAYPGNLTYTWYWQDENVYFQNDLKLRVRILIDGTLIIFRVKPEDAGKYTCVPS 306

  Fly   248 NVVGKDTAD----TFVYP--VLN 264
            |.:|:..:.    |..||  |||
  Rat   307 NSLGRSPSASAYLTVQYPARVLN 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	21/67 (31%)
Igsf9b	NP_001363879.1	PHA03247	<898..1246	CDD:223021
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	918..1044
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1111..1332
		Ig	41..115	CDD:319273
		I-set	139..225	CDD:369462	28/112 (25%)
		Ig	229..321	CDD:386229	23/91 (25%)
		Ig	<353..414	CDD:386229
		Ig	438..502	CDD:319273
		FN3	510..605	CDD:238020
		FN3	621..703	CDD:238020
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	762..821
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900