DRSC/TRiP Functional Genomics Resources

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Protein Alignment ImpL2 and Lrit1

DIOPT Version :9

Sequence 1:NP_728961.2 Gene:ImpL2 / 38513 FlyBaseID:FBgn0001257 Length:267 Species:Drosophila melanogaster
Sequence 2:NP_647547.2 Gene:Lrit1 / 246214 RGDID:628607 Length:623 Species:Rattus norvegicus


Alignment Length:282 Identity:55/282 - (19%)
Similarity:103/282 - (36%) Gaps:65/282 - (23%)


- Green bases have known domain annotations that are detailed below.


  Fly    41 IEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQW-VVGHLPRSELDD 104
            :..|..:|.:| .|..||.:............|........:.|:.:.:..| .:...|:.:|.|
  Rat    74 VPGETFRPLSR-LEQLWLPYNALSELSTLMLRGLRRLRELRLPGNHLVTFPWAALKDTPQLQLLD 137

  Fly   105 LDSNQVAEEAPSAIVRVRSSHIID------------------HV-----LSEARTYTCVGRTGSK 146
            |.:|:::...|.|:..:.:...:|                  |:     ||..||...:|...:.
  Rat   138 LQANRLSTLPPEAVHFLENLTFLDLSNNQLMRLPEELLDTWAHLKTGPYLSSRRTRLVLGLQDNP 202

  Fly   147 TI--------------YASTVVH--------PPRS------SRLTPEKTYPGAQKPRIIYTEKTH 183
            .:              :||.::.        .|||      |:|...|    .|.|.:.....:.
  Rat   203 WVCDCRLYDLVHLLDGWASNLIFIEARLRCGSPRSLAGVAFSQLELRK----CQSPELRPGVTSI 263

  Fly   184 LDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHRHR-VLANGD----LLISEIKWEDMGNYK 243
            :..:||.:.|.|.....|..|::| ...|...:.|..|: |.::|.    |.:..:...|.|:|.
  Rat   264 ISPLGSTVLLRCGATGIPGPEMSW-RRANGRPLNGTVHQEVSSDGSSWTLLDLPVVSLFDSGDYI 327

  Fly   244 CIARNVVGKDTADTFVYPVLNE 265
            |.|:|.:|  .::|.:..::.|
  Rat   328 CQAKNFLG--ASETLISLIVTE 347

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ImpL2NP_728961.2 IGc2 187..251 CDD:197706 19/68 (28%)
Lrit1NP_647547.2 LRRNT 23..61 CDD:214470
LRR 1 60..81 1/6 (17%)
LRR_8 63..143 CDD:290566 14/69 (20%)
leucine-rich repeat 64..84 CDD:275378 2/9 (22%)
LRR 2 84..105 4/21 (19%)
leucine-rich repeat 85..132 CDD:275378 6/46 (13%)
LRR 3 108..128 2/19 (11%)
LRR_8 131..>176 CDD:290566 8/44 (18%)
LRR_4 131..172 CDD:289563 8/40 (20%)
LRR 4 132..153 6/20 (30%)
leucine-rich repeat 133..156 CDD:275378 6/22 (27%)
LRR 5 156..177 1/20 (5%)
leucine-rich repeat 157..180 CDD:275378 1/22 (5%)
leucine-rich repeat 181..205 CDD:275378 5/23 (22%)
TPKR_C2 201..>240 CDD:301599 5/38 (13%)
Ig 257..345 CDD:299845 21/90 (23%)
IG_like 267..345 CDD:214653 21/80 (26%)
FN3 431..501 CDD:214495
LRR 6 525..548
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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