DRSC/TRiP Functional Genomics Resources

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Protein Alignment ImpL2 and Ncam1

DIOPT Version :9

Sequence 1:NP_728961.2 Gene:ImpL2 / 38513 FlyBaseID:FBgn0001257 Length:267 Species:Drosophila melanogaster
Sequence 2:XP_038936733.1 Gene:Ncam1 / 24586 RGDID:67378 Length:1136 Species:Rattus norvegicus


Alignment Length:267 Identity:70/267 - (26%)
Similarity:105/267 - (39%) Gaps:65/267 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    32 DDSND-----VDNSIEAEEE-KPRNRAFEAD---WLK-FTKTPPTKLQQADGATIE----IVCEM 82
            |||::     ||.:.|||.. ...|:|.|.|   .|| |.|...|.::......:|    :.||.
  Rat   268 DDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEA 332

  Fly    83 MGSQVPSIQWVVGHLPRSELDDLDSNQVA-------EEAPSAIVRVRSSHIIDHVLSEARTYTCV 140
            .|..:|||.|      |:...::.|.:.|       :|.....:.|||...:..:..::..||..
  Rat   333 SGDPIPSITW------RTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDA 391

  Fly   141 GR---TGSKTIYASTVVHPPRSSRLTPEKTY-PGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARP 201
            |.   |.|.||...       |..:..|..| |..|.|..:||.:      |:.:.:.|.|.|.|
  Rat   392 GEYICTASNTIGQD-------SQSMYLEVQYAPKLQGPVAVYTWE------GNQVNITCEVFAYP 443

  Fly   202 RAEITWL---------NNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDT--- 254
            .|.|:|.         |..|.:|     :...:...|.::.....|.|||.|.|.|.:|:::   
  Rat   444 SATISWFRDGQLLPSSNYSNIKI-----YNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEF 503

  Fly   255 ----ADT 257
                |||
  Rat   504 ILVQADT 510

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ImpL2NP_728961.2 IGc2 187..251 CDD:197706 19/72 (26%)
Ncam1XP_038936733.1 IgI_1_NCAM-1 20..116 CDD:409451
Ig strand B 37..41 CDD:409451
Ig strand C 51..55 CDD:409451
Ig strand E 79..83 CDD:409451
Ig strand F 93..98 CDD:409451
Ig strand G 107..110 CDD:409451
IG_like 124..190 CDD:214653
Ig strand B 135..139 CDD:409353
Ig strand C 148..152 CDD:409353
Ig strand E 172..176 CDD:409353
Ig strand F 186..191 CDD:409353
IgI_3_NCAM-1 211..308 CDD:143207 15/39 (38%)
Ig strand B 231..235 CDD:143207
Ig strand C 244..248 CDD:143207
Ig strand E 271..275 CDD:143207 0/3 (0%)
Ig strand F 285..290 CDD:143207 1/4 (25%)
Ig strand G 298..301 CDD:143207 1/2 (50%)
IgI_NCAM-1 307..413 CDD:143277 25/118 (21%)
Ig strand B 326..330 CDD:143277 0/3 (0%)
Ig strand C 339..343 CDD:143277 3/9 (33%)
Ig strand E 379..383 CDD:143277 0/3 (0%)
Ig strand F 393..398 CDD:143277 0/4 (0%)
Ig strand G 406..409 CDD:143277 1/2 (50%)
Ig_3 422..494 CDD:404760 21/82 (26%)
Ig strand B 433..437 CDD:409353 0/3 (0%)
Ig strand C 446..450 CDD:409353 1/3 (33%)
Ig strand E 473..477 CDD:409353 1/3 (33%)
Ig strand F 487..492 CDD:409353 3/4 (75%)
FN3 509..606 CDD:238020 2/2 (100%)
fn3 619..701 CDD:394996
Herpes_BLLF1 <842..1133 CDD:282904
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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