DRSC/TRiP Functional Genomics Resources

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Protein Alignment ImpL2 and Lrit1

DIOPT Version :9

Sequence 1:NP_728961.2 Gene:ImpL2 / 38513 FlyBaseID:FBgn0001257 Length:267 Species:Drosophila melanogaster
Sequence 2:NP_666357.2 Gene:Lrit1 / 239037 MGIID:2385320 Length:624 Species:Mus musculus


Alignment Length:253 Identity:54/253 - (21%)
Similarity:92/253 - (36%) Gaps:54/253 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 PRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGSQVPSIQWVVGH-LPRSELDDLDSNQVA 111
            |.||.....|.....||..:|           .::..:::.::.....| |......||.:||:.
Mouse   115 PGNRLVTFPWAALRDTPQLQL-----------LDLQANRLSTLPPEAAHFLENLTFLDLSNNQLM 168

  Fly   112 EEAPSAIVRV---------RSSHIIDHVLS--------EARTYTCV----GRTGSKTIYASTVVH 155
             ..|..::.|         .|.|....:|.        :.|.|..|    |...|..|:....:.
Mouse   169 -RLPEELLDVWAHLKTGPFLSGHHARLILGLQDNPWVCDCRLYDLVHLLDGWVSSNLIFIEARLR 232

  Fly   156 --PPRS------SRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNEN 212
              .|||      |:|...|    .|.|.:.....:.:..:||.:.|.|.....|..|::| ...|
Mouse   233 CASPRSLAGVAFSQLELRK----CQSPELRPGVTSIISPLGSTVLLRCGATGIPGPEMSW-RRAN 292

  Fly   213 KEIVQGHRHR-VLANGD----LLISEIKWEDMGNYKCIARNVVGKDTADTFVYPVLNE 265
            ...:.|..|: |.::|.    |.:..:...|.|:|.|.|:|.:|  .::|.:..::.|
Mouse   293 GRPLNGTVHQEVSSDGSSWTLLDLPVVSLFDSGDYICQAKNFLG--ASETLISLIVTE 348

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ImpL2NP_728961.2 IGc2 187..251 CDD:197706 19/68 (28%)
Lrit1NP_666357.2 LRRNT 23..61 CDD:214470
LRR 1 60..81
LRR_8 63..143 CDD:290566 7/38 (18%)
leucine-rich repeat 64..84 CDD:275378
LRR 2 84..105
leucine-rich repeat 85..132 CDD:275378 5/16 (31%)
LRR 3 108..129 4/13 (31%)
LRR_8 131..>176 CDD:290566 9/56 (16%)
LRR_4 131..172 CDD:289563 8/52 (15%)
LRR 4 132..153 1/31 (3%)
leucine-rich repeat 133..156 CDD:275378 3/33 (9%)
LRR 5 156..177 5/21 (24%)
leucine-rich repeat 157..180 CDD:275378 6/23 (26%)
leucine-rich repeat 181..205 CDD:275378 3/23 (13%)
TPKR_C2 201..>241 CDD:301599 9/39 (23%)
Ig 258..346 CDD:299845 21/90 (23%)
IG_like 268..346 CDD:214653 21/80 (26%)
FN3 432..502 CDD:214495
LRR 6 526..549
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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