DRSC/TRiP Functional Genomics Resources

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Protein Alignment ImpL2 and Iglon5

DIOPT Version :9

Sequence 1:NP_728961.2 Gene:ImpL2 / 38513 FlyBaseID:FBgn0001257 Length:267 Species:Drosophila melanogaster
Sequence 2:NP_001157990.1 Gene:Iglon5 / 210094 MGIID:2686277 Length:336 Species:Mus musculus


Alignment Length:204 Identity:43/204 - (21%)
Similarity:69/204 - (33%) Gaps:67/204 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    72 DGATIEIVCEMMGSQVPSIQWVVGHLPRSELDDLDS-NQVAEEAPSAIVRVRSSHIIDHVLSEAR 135
            :|..:.::|..:|...|::.|      |...|...| .::.|             |.|....:|.
Mouse   146 EGGNVNLLCLAVGRPEPTVTW------RQLRDGFTSEGEILE-------------ISDIQRGQAG 191

  Fly   136 TYTCVGRTGSKTIYAS-----TVVHPPRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPC 195
            .|.||...|..:...|     ||.:||..:.:|..:|                  .:|....|.|
Mouse   192 EYECVTHNGVNSAPDSRRVLVTVNYPPTITDVTSART------------------ALGRAALLRC 238

  Fly   196 RVHARPRAEITWLNNENKEIVQGHRHRVLANGD--------------LLISEIKWEDMGNYKCIA 246
            ...|.|.|:..|..::          |:|::|.              ||.:.:.....|||.|.|
Mouse   239 EAMAVPPADFQWYKDD----------RLLSSGSAEGLKVQTERTRSMLLFANVSARHYGNYTCRA 293

  Fly   247 RNVVGKDTA 255
            .|.:|..:|
Mouse   294 ANRLGASSA 302

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ImpL2NP_728961.2 IGc2 187..251 CDD:197706 18/77 (23%)
Iglon5NP_001157990.1 Ig 41..129 CDD:416386
Ig strand A' 41..46 CDD:409353
Ig strand B 48..56 CDD:409353
CDR1 56..60 CDD:409353
FR2 61..68 CDD:409353
Ig strand C 61..67 CDD:409353
CDR2 69..79 CDD:409353
Ig strand C' 71..74 CDD:409353
Ig strand C' 76..79 CDD:409353
FR3 80..115 CDD:409353
Ig strand D 84..91 CDD:409353
Ig strand E 94..100 CDD:409353
Ig strand F 107..115 CDD:409353
CDR3 116..120 CDD:409353
Ig strand G 120..129 CDD:409353
FR4 122..129 CDD:409353
Ig strand A 132..137 CDD:409353
Ig_3 134..199 CDD:404760 15/71 (21%)
Ig strand A' 140..145 CDD:409353
Ig strand B 148..157 CDD:409353 1/8 (13%)
Ig strand C 163..167 CDD:409353 1/9 (11%)
Ig strand D 174..177 CDD:409353 1/2 (50%)
Ig strand E 178..183 CDD:409353 1/17 (6%)
Ig strand F 191..199 CDD:409353 3/7 (43%)
Ig_3 217..295 CDD:404760 21/105 (20%)
putative Ig strand A 218..224 CDD:409353 1/5 (20%)
Ig strand B 234..238 CDD:409353 1/3 (33%)
Ig strand C 247..251 CDD:409353 0/3 (0%)
Ig strand E 274..278 CDD:409353 1/3 (33%)
Ig strand F 288..293 CDD:409353 3/4 (75%)
Ig strand G 301..304 CDD:409353 1/2 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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