DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ImpL2 and Ncam1

DIOPT Version :9

Sequence 1:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	XP_006510118.1	Gene:	Ncam1 / 17967	MGIID:	97281	Length:	1162	Species:	Mus musculus

Alignment Length:	267	Identity:	70/267 - (26%)
Similarity:	105/267 - (39%)	Gaps:	65/267 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 DDSND-----VDNSIEAEEE-KPRNRAFEAD---WLK-FTKTPPTKLQQADGATIE----IVCEM 82
            |||::     ||.:.|||.. ...|:|.|.|   .|| |.|...|.::......:|    :.||.
Mouse   268 DDSSELTIRNVDKNDEAEYVCIAENKAGEQDASIHLKVFAKPKITYVENQTAMELEEQVTLTCEA 332

  Fly    83 MGSQVPSIQWVVGHLPRSELDDLDSNQVA-------EEAPSAIVRVRSSHIIDHVLSEARTYTCV 140
            .|..:|||.|      |:...::.|.:.|       :|.....:.|||...:..:..::..||..
Mouse   333 SGDPIPSITW------RTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDA 391

  Fly   141 GR---TGSKTIYASTVVHPPRSSRLTPEKTY-PGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARP 201
            |.   |.|.||...       |..:..|..| |..|.|..:||.:      |:.:.:.|.|.|.|
Mouse   392 GEYICTASNTIGQD-------SQSMYLEVQYAPKLQGPVAVYTWE------GNQVNITCEVFAYP 443

  Fly   202 RAEITWL---------NNENKEIVQGHRHRVLANGDLLISEIKWEDMGNYKCIARNVVGKDT--- 254
            .|.|:|.         |..|.:|     :...:...|.::.....|.|||.|.|.|.:|:::
Mouse   444 SATISWFRDGQLLPSSNYSNIKI-----YNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEF 503

  Fly   255 ----ADT 257
                |||
Mouse   504 ILVQADT 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	19/72 (26%)
Ncam1	XP_006510118.1	Ig1_NCAM-1	20..115	CDD:143273
		IG	124..190	CDD:214652
		Ig3_NCAM-1_like	211..308	CDD:143207	15/39 (38%)
		Ig_NCAM-1	307..413	CDD:143277	25/118 (21%)
		Ig_3	417..494	CDD:372822	23/87 (26%)
		FN3	509..606	CDD:238020	2/2 (100%)
		fn3	649..731	CDD:365830
		PHA03247	<905..1140	CDD:223021
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900