| Sequence 1: | NP_002263.3 | Gene: | KRT4 / 3851 | HGNCID: | 6441 | Length: | 520 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_510649.3 | Gene: | ifa-3 / 181699 | WormBaseID: | WBGene00002051 | Length: | 581 | Species: | Caenorhabditis elegans |
| Alignment Length: | 432 | Identity: | 106/432 - (24%) |
|---|---|---|---|
| Similarity: | 195/432 - (45%) | Gaps: | 84/432 - (19%) |
- Green bases have known domain annotations that are detailed below.
|
Human 105 PAGGIQEVTINQSLLTPLHVE-----IDP-------EIQKVRTEEREQIKLLNNKFASFIDKVQF 157
Human 158 LEQQNKVLETKWNLLQQQTTTTSSKNLEPLFETYLSVLRKQLDTLGNDKGRLQSELKTMQDSVED 222
Human 223 FKTKYEE------------------------EIN--KRTAA--ENDFVVLKK------------- 246
Human 247 -DVDAAYLNKVELEAKVDSLNDEINFLKVLYDAELSQMQTHVS-DTSVVLSMDNNRNL---DLDS 306
Human 307 IIAEVRAQYEEIAQRSKAEAEALYQTKVQQLQISVDQHG-------DNLKNTKSEIAELNRMIQR 364
Human 365 LRAEIENIKKQCQTLQVSVADAEQRGENALKDAHSKRVELEAALQQAKEELARMLREYQELMSVK 429
Human 430 LALDIEIATYRKLLEG--EEYRMSGECQSAVSISVVSGSTST 469 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| KRT4 | NP_002263.3 | Head | 1..136 | 9/42 (21%) | |
| Keratin_2_head | 14..133 | CDD:406589 | 8/39 (21%) | ||
| Filament | 136..449 | CDD:365827 | 94/367 (26%) | ||
| Coil 1A | 137..172 | 16/34 (47%) | |||
| Linker 1 | 173..191 | 3/17 (18%) | |||
| Coil 1B | 192..284 | 27/133 (20%) | |||
| Linker 12 | 285..307 | 5/25 (20%) | |||
| Coil 2 | 308..447 | 39/147 (27%) | |||
| Tail | 448..520 | 3/22 (14%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 500..520 | ||||
| ifa-3 | NP_510649.3 | Filament | 71..419 | CDD:278467 | 90/360 (25%) |
| DUF342 | <140..209 | CDD:302792 | 15/68 (22%) | ||
| DUF904 | 181..245 | CDD:283624 | 15/63 (24%) | ||
| LTD | 462..570 | CDD:279300 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 181 | 1.000 | Domainoid score | I2296 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X62 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.910 | |||||