Protein Alignment Ero1L and ERO1

DIOPT Version :10

• Sequence 1: NP_647865.2
• Gene: Ero1L / 38500
• FlyBaseID: FBgn0261274
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_013576.1
• Gene: ERO1 / 854909
• SGDID: S000004599
• Length: 563
• Species: Saccharomyces cerevisiae
• Alignment Length: 481
• Identity: 147/481 - (30%)
• Similarity: 248/481 - (51%)
• Gaps: 84/481 - (17%)

  Fly    13 SAAVVLVLLLLWTDTTGGYFAAIDETETSKN--CFCELEGSIND---CSCDVDTVDHFN--NMKI 70
            :|...|.|....:.|:...:.|.|:|:.:.|  .||:::.  ||   .||:| |.:..|  |..|
Yeast     5 TAIATLCLTAFTSATSNNSYIATDQTQNAFNDTHFCKVDR--NDHVSPSCNV-TFNELNAINENI 66

  Fly    71 YPRLQSLLVKNFFRFYKVNLRQECPFW-PDDSRCAMRFCQVENCEE-QAIPQGIKDKGEHKEKAA 133
            ...|.:||..:||::::::|.::|.|| .:|..|..|.|.|:..|: ..:|:
Yeast    67 RDDLSALLKSDFFKYFRLDLYKQCSFWDANDGLCLNRACSVDVVEDWDTLPE------------- 118

  Fly   134 FKYTREAQVG---GSACSDGEDFDSSLGFLDTSISDQAHREFELWAKHDEAEEDFCIVDD-HEEG 194
              |.:...:|   .....:.:|.|....||| .:...:.:..::     |...::|.|:| :.:.
Yeast   119 --YWQPEILGSFNNDTMKEADDSDDECKFLD-QLCQTSKKPVDI-----EDTINYCDVNDFNGKN 175

  Fly   195 SQYVDLLLNPERYTGYKGESAHRIWKSIYLENCF--GGNNETANKFSNYVPHLDLRNVCLEQRAF 257
            :..:||..||||:|||.|:.|.:||.:||.:|||  |...|:                 |.:.||
Yeast   176 AVLIDLTANPERFTGYGGKQAGQIWSTIYQDNCFTIGETGES-----------------LAKDAF 223

  Fly   258 YRIISGLHSSINIHLCSKYLLSESKDFLDPQGIWGPNVKEFKRRFSPETTSGEGPHWLRNLYFIY 322
            ||::||.|:||..||..:||.:::       |.|.||:..|..|.      |..|..:.|:||.|
Yeast   224 YRLVSGFHASIGTHLSKEYLNTKT-------GKWEPNLDLFMARI------GNFPDRVTNMYFNY 275

  Fly   323 LIELRALAKAAPYLRREDYYTGIAEEDDEVKLAINDMLSVIENFQSHFDENALFSNGIASIKFKH 387
            .:..:||.|..|||....:...:   :.|:|..:::::|.::.  ..|:|:.:|:|.: |:..|.
Yeast   276 AVVAKALWKIQPYLPEFSFCDLV---NKEIKNKMDNVISQLDT--KIFNEDLVFANDL-SLTLKD 334

  Fly   388 DYKEKFRNISRIMSCVGCDKCKLWGKLQTQGLGTALKILYSEKLNLATESGLWDKPHIEADPIFR 452
            :::.:|:|:::||.||.||:|:||||:||.|..||||||:  ::|.|.|   :.|.||    :.:
Yeast   335 EFRSRFKNVTKIMDCVQCDRCRLWGKIQTTGYATALKILF--EINDADE---FTKQHI----VGK 390

  Fly   453 LSRTEIVALFNAFGRLSNSIYEMENF 478
            |::.|::||...|||||.||..:..|
Yeast   391 LTKYELIALLQTFGRLSESIESVNMF 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ero1L	NP_647865.2	ERO1	69..475	CDD:461191	128/413 (31%)
ERO1	NP_013576.1	ERO1	8..526	CDD:227393	146/478 (31%)