Protein Alignment Ero1L and ero1b

DIOPT Version :9

• Sequence 1: NP_647865.2
• Gene: Ero1L / 38500
• FlyBaseID: FBgn0261274
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: XP_005173001.1
• Gene: ero1b / 767700
• ZFINID: ZDB-GENE-060929-744
• Length: 488
• Species: Danio rerio
• Alignment Length: 520
• Identity: 231/520 - (44%)
• Similarity: 308/520 - (59%)
• Gaps: 72/520 - (13%)

  Fly     1 MTTRTVQRNLWASAAVVLVLLLLWTDTTGGYFAA-------------------IDETETSKNCFC 46
            |..||....|     |:|:.|:.      |||.:                   ..|.|..::|.|
Zfish     1 MLHRTQTHGL-----VILMSLIC------GYFCSGWFQNNAKSKSTQKEPVYGHTEDELDQSCLC 54

  Fly    47 ELEGSINDCSCDVDTVDHFNNMKIYPRLQSLLVKNFFRFYKVNLRQECPFWPDDSRCAMRFCQVE 111
            .|.|.::||.||::::|.|||.||||.::.|..::|||:|||||::.||||||||.|:::.|.||
Zfish    55 HLTGVLDDCFCDIESIDVFNNFKIYPHIRKLTERDFFRYYKVNLKRPCPFWPDDSHCSIKDCHVE 119

  Fly   112 NCEEQAIPQGIKDKGEHKEKAAFKYTREAQVGGSACSDGEDFDSSLGFLDTSISDQAHREFELWA 176
            .|.|..:|.|||....:|...|.....|.:    .|....:    ||.:::::|:|:...|..||
Zfish   120 PCPESKVPVGIKSGNYNKYSHAANTVSEMR----ECEQAHE----LGAINSTLSNQSKEAFADWA 176

  Fly   177 KHDEAEEDFCIVDDH-EEGSQYVDLLLNPERYTGYKGESAHRIWKSIYLENCFG----------- 229
            .||:|::.||.:||. ...|:||||||||||||||||.||.|:|.|||.||||.
Zfish   177 HHDDAQDHFCGLDDEMSPESEYVDLLLNPERYTGYKGPSAWRVWNSIYEENCFKPRSVYRPLNPL 241

  Fly   230 ---GNNETANKFSNYVPHLDLRNVCLEQRAFYRIISGLHSSINIHLCSKYLLSESKDFLDPQGIW 291
               ..::....|.|:     |..:|||:|.|||:|||||||||||||:||||.|...    :.:|
Zfish   242 APVRGDDDGEGFYNW-----LEGLCLEKRVFYRLISGLHSSINIHLCAKYLLDEGWG----KPVW 297

  Fly   292 GPNVKEFKRRFSPETTSGEGPHWLRNLYFIYLIELRALAKAAPYLRRE--DYYTGIAEEDDEVKL 354
            ||||.||::||.|..|.|||...|:||||:||||||||:|.|||..|.  :.|||..|||...|.
Zfish   298 GPNVHEFRQRFDPAETKGEGTRRLKNLYFLYLIELRALSKVAPYFERSFINLYTGNTEEDTSTKQ 362

  Fly   355 AINDMLSVIENFQSHFDENALFS-NGIASIKFKHDYKEKFRNISRIMSCVGCDKCKLWGKLQTQG 418
            .:.::|:..:.|..||||:::|: :.|.|...|.:::..|:||||||.||||.||:|||||||||
Zfish   363 LLLEILNETKAFPMHFDESSMFAGHKIESKTLKEEFRLHFKNISRIMDCVGCSKCRLWGKLQTQG 427

  Fly   419 LGTALKILYSEKLNLATESGLWDKPHIEADPIFRLSRTEIVALFNAFGRLSNSIYEMENFRCVLR 483
            |||||:||:|||       .:...|.......|:|:|.|||||.|.|.|||.||.|:.|||.:|:
Zfish   428 LGTALRILFSEK-------EIKKLPENSPSKGFQLTRQEIVALLNGFSRLSTSIKELHNFRTLLK 485

  Fly   484  483
            Zfish   486  485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ero1L	NP_647865.2	ERO1	69..473	CDD:282050	201/421 (48%)
ero1b	XP_005173001.1	ERO1	77..475	CDD:282050	201/421 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596032
Domainoid	1	1.000	376	1.000	Domainoid score	I826
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H8740
Inparanoid	1	1.050	413	1.000	Inparanoid score	I1813
OMA	1	1.010	-	-		QHG54085
OrthoDB	1	1.010	-	-		D1181226at2759
OrthoFinder	1	1.000	-	-		FOG0001495
OrthoInspector	1	1.000	-	-		otm25410
orthoMCL	1	0.900	-	-		OOG6_101008
Panther	1	1.100	-	-	LDO	PTHR12613
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R413
SonicParanoid	1	1.000	-	-		X1065
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	14	13.940