Protein Alignment Ero1L and Ero1a

DIOPT Version :10

• Sequence 1: NP_647865.2
• Gene: Ero1L / 38500
• FlyBaseID: FBgn0261274
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_056589.1
• Gene: Ero1a / 50527
• MGIID: 1354385
• Length: 464
• Species: Mus musculus
• Alignment Length: 460
• Identity: 223/460 - (48%)
• Similarity: 302/460 - (65%)
• Gaps: 47/460 - (10%)

  Fly    41 SKNCFCELEGSINDCSCDVDTVDHFNNMKIYPRLQSLLVKNFFRFYKVNLRQECPFWPDDSRCAM 105
            ::.|||::.|.::||:|||:|:|.|||.:::||||.||..::||:|||||::.||||.|.::|..
Mouse    32 AQRCFCQVSGYLDDCTCDVETIDKFNNYRLFPRLQKLLESDYFRYYKVNLKKPCPFWNDINQCGR 96

  Fly   106 RFCQVENCEEQAIPQGIKDKGEHKEKAAFKYTREAQVGGSACSDGEDFDSSLGFLDTSISDQAHR 170
            |.|.|:.|....:|.|||       .|::||:.||. ....|...|    .||.:|.|:|::..:
Mouse    97 RDCAVKPCHSDEVPDGIK-------SASYKYSEEAN-RIEECEQAE----RLGAVDESLSEETQK 149

  Fly   171 EFELWAKHDEAEEDFCIVDD-HEEGSQYVDLLLNPERYTGYKGESAHRIWKSIYLENCF------ 228
            ....|.|||::.:.||.:|| ....::||||||||||||||||..|.|||..||.||||
Mouse   150 AVLQWTKHDDSSDSFCEIDDIQSPDAEYVDLLLNPERYTGYKGPDAWRIWSVIYEENCFKPQTIQ 214

  Fly   229 -----GGNNETANKFSNYVPHLDLRNVCLEQRAFYRIISGLHSSINIHLCSKYLLSESKDFLDPQ 288
                 |......|.|.|:     |..:|:|:|||||:|||||:|||:||.::|||.::  :|:.:
Mouse   215 RPLASGRGKSKENTFYNW-----LEGLCVEKRAFYRLISGLHASINVHLSARYLLQDT--WLEKK 272

  Fly   289 GIWGPNVKEFKRRFSPETTSGEGPHWLRNLYFIYLIELRALAKAAPYLRREDY--YTGIAEEDDE 351
              ||.||.||::||....|.||||..||||||:||||||||:|..|:..|.|:  :||...:|.|
Mouse   273 --WGHNVTEFQQRFDGILTEGEGPRRLRNLYFLYLIELRALSKVLPFFERPDFQLFTGNKVQDAE 335

  Fly   352 VKLAINDMLSVIENFQSHFDENALFS-NGIASIKFKHDYKEKFRNISRIMSCVGCDKCKLWGKLQ 415
            .|..:.::|..|::|..|||||:.|: :...:.|.|.|::..||||||||.||||.||:||||||
Mouse   336 NKALLLEILHEIKSFPLHFDENSFFAGDKNEAHKLKEDFRLHFRNISRIMDCVGCFKCRLWGKLQ 400

  Fly   416 TQGLGTALKILYSEKL--NLATESGLWDKPHIEADPIFRLSRTEIVALFNAFGRLSNSIYEMENF 478
            |||||||||||:||||  |: .|||    |..|    |:|:|.|||:|||||||:|.|:.|:|||
Mouse   401 TQGLGTALKILFSEKLIANM-PESG----PSYE----FQLTRQEIVSLFNAFGRISTSVRELENF 456

  Fly   479 RCVLR 483
            |.:|:
Mouse   457 RHLLQ 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ero1L	NP_647865.2	ERO1	69..475	CDD:461191	203/422 (48%)
Ero1a	NP_056589.1	ERO1	60..453	CDD:461191	203/422 (48%)