Protein Alignment Ero1L and ero1a

DIOPT Version :9

• Sequence 1: NP_647865.2
• Gene: Ero1L / 38500
• FlyBaseID: FBgn0261274
• Length: 483
• Species: Drosophila melanogaster
• Sequence 2: NP_956644.2
• Gene: ero1a / 393321
• ZFINID: ZDB-GENE-040426-1312
• Length: 461
• Species: Danio rerio
• Alignment Length: 493
• Identity: 225/493 - (45%)
• Similarity: 308/493 - (62%)
• Gaps: 68/493 - (13%)

  Fly    17 VLVLLLLWTD---TTGGYFAAIDETETSKNCFCELEGSINDCSCDVDTVDHFNNMKIYPRLQSLL 78
            ||:|.|..|.   ||.|        ..:..|||::.|:::||:|||:|:|.|||..|:|:||.||
Zfish     5 VLLLGLFLTSVHVTTAG--------SAAHRCFCQVTGTLDDCACDVETIDKFNNKDIFPKLQKLL 61

  Fly    79 VKNFFRFYKVNLRQECPFWPDDSRCAMRFCQVENCEEQAIPQGIKDKGEHKEKAAFKYTREAQVG 143
            ..::||||||||...||||.|.|:|.:::|.|:.|....:|:|:|       .:::||:.:|...
Zfish    62 SSDYFRFYKVNLNNGCPFWTDHSQCGLKYCAVKPCSPDEVPEGLK-------SSSYKYSEKASHD 119

  Fly   144 GSACSDGEDFDSSLGFLDTSISDQAHREFELWAKHDEAEEDFCIVDDHEE-GSQYVDLLLNPERY 207
            ...|...|    .||.::.|:||:..:..:.|.|:|:..:.||::||.:. .||||||||||||:
Zfish   120 TEECEKAE----KLGAVNGSLSDETRQALQEWKKYDDESDRFCMLDDEDSPESQYVDLLLNPERF 180

  Fly   208 TGYKGESAHRIWKSIYLENCF-------------GGNNETANKFSNYVPHLDLRNVCLEQRAFYR 259
            |||.|..|.|||.|||.||||             ..:.:....|..:     |..:|:|:|||:|
Zfish   181 TGYIGAEAWRIWNSIYEENCFKPYSVNRPLNPLASNSGDDGQGFYRW-----LEGLCVEKRAFFR 240

  Fly   260 IISGLHSSINIHLCSKYLLSESKDFLDPQGIWGPNVKEFKRRFSPETTSGEGPHWLRNLYFIYLI 324
            :|||||:||||||.::|||.|  ::.:.:  ||.||.||::||..:.|.||||..||||||:|||
Zfish   241 LISGLHASINIHLSARYLLDE--NWFEMK--WGHNVSEFQQRFDEDLTKGEGPKRLRNLYFLYLI 301

  Fly   325 ELRALAKAAPYLRREDY--YTGIAEEDDEVKLAINDMLSVIENFQSHFDENALFS-NGIASIKFK 386
            |||||||..||..|..:  |||...:||:.|..:.::|.|.::|..||||.|||: |...::|.|
Zfish   302 ELRALAKILPYFERSTFQLYTGQDTQDDQNKKLLLELLHVAKSFPLHFDETALFAGNNKEAMKLK 366

  Fly   387 HDYKEKFRNISRIMSCVGCDKCKLWGKLQTQGLGTALKILYSEKLNLATESGLWDKPHIEA---- 447
            .|:|..|:||||||.||.|.||:|||||||||||||||||:||:             .|||
Zfish   367 EDFKLTFKNISRIMDCVECFKCRLWGKLQTQGLGTALKILFSER-------------QIEAMPNT 418

  Fly   448 ---DPIFRLSRTEIVALFNAFGRLSNSIYEMENFRCVL 482
               :|.|:|||.|||:|||||||:|.|:.|::|||.:|
Zfish   419 SNTNPSFQLSRQEIVSLFNAFGRISTSVRELKNFRSLL 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ero1L	NP_647865.2	ERO1	69..473	CDD:282050	198/427 (46%)
ero1a	NP_956644.2	ERO1	52..447	CDD:282050	198/427 (46%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170596033
Domainoid	1	1.000	376	1.000	Domainoid score	I826
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	413	1.000	Inparanoid score	I1813
OMA	1	1.010	-	-		QHG54085
OrthoDB	1	1.010	-	-		D1181226at2759
OrthoFinder	1	1.000	-	-		FOG0001495
OrthoInspector	1	1.000	-	-		otm25410
orthoMCL	1	0.900	-	-		OOG6_101008
Panther	1	1.100	-	-	O	PTHR12613
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1065
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910