DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment mas and CG7432

DIOPT Version :9

Sequence 1:	NP_523919.1	Gene:	mas / 38499	FlyBaseID:	FBgn0011653	Length:	1047	Species:	Drosophila melanogaster
Sequence 2:	NP_650825.2	Gene:	CG7432 / 42347	FlyBaseID:	FBgn0038727	Length:	721	Species:	Drosophila melanogaster

Alignment Length:	926	Identity:	209/926 - (22%)
Similarity:	306/926 - (33%)	Gaps:	331/926 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   211 TSDGLCKEGTKCCVSLDEYSNGKLPKDIYIPAKHMSNLKPNQTLSEKSAPAKSSSTSTTSTTTTT 275
            |:.|....|.      ||.....|..|......|:.:.:..:.|.|..|.::||::|.:|.::.:
  Fly    23 TAQGQSDAGN------DEEQPLHLTNDASFFQPHLHDRRLGRQLIEDLAESQSSASSVSSGSSQS 81

  Fly   276 STTTTPEPARINNSSPKPTKHKKHPTTTTTEAAEEEEEQETEEDGEEEEPP--LS----NKLKSG 334
            .:....:...:..||               |..:.:|||   .:|..|..|  ||    |::...
  Fly    82 GSAYEDDDDDVEGSS---------------EYYDSDEEQ---SEGSNESLPRLLSQSTFNRISET 128

  Fly   335 QGQ--------------GQVLKECEGECMNGIFAIFCDDIDSDAFCPGEESCCVTGGASEATPSS 385
            .|.              ||...:.||       |...:|...|    ..:|    ||:|.||.|:
  Fly   129 LGALNHVGHMLVDITRGGQDQAKMEG-------AEKSEDTSQD----NSQS----GGSSSATASA 178

  Fly   386 KAPPTKPAIKHAPKPAAKPARPASPPPAPPSSTSGGGGGGDFL----SQIISFAESTLNSPSPPP 446
                                  :|.....|||||...|..:.|    .:::.....||::.|..|
  Fly   179 ----------------------SSTTEVVPSSTSSPRGNSEQLPGVSDKLMDPLPITLSANSLLP 221

  Fly   447 ---PPPQAPIQV--------PRCPGFC-----------LLNIMAAFCERPS---VLVSTPTTCAK 486
               |...:.|||        ...|.|.           ..|......::||   |||..    |:
  Fly   222 AGKPANLSVIQVATKRIGMDDSAPMFVENKELKLKKKKKKNKNKQKVKKPSEEGVLVPV----AQ 282

  Fly   487 GSVCCDNSRAGAPKPKLP--PPTPSPTASPTAPPYVLP---------------------NTPSPD 528
            |      ::....|.|:|  |.|.:.:.:..||..:.|                     .||| .
  Fly   283 G------AQQSQQKIKIPTTPRTTTTSTTTEAPITLTPLDQLAEASDEAGTGKDVENYCKTPS-G 340

  Fly   529 PREECP--GSCIVSLLSFT------CFKNAEMTDLFRCKRSGQICC--APKSKILEKQ---QFQT 580
            .|..|.  .||...||:.:      |||:..:..         :||  :..|.:|..|   :..|
  Fly   341 RRGRCEDLSSCPALLLNLSSLRESLCFKSLYVPG---------VCCPISSSSTVLTTQKPLRLTT 396

  Fly   581 RNDTAYYPAPPPPPIGPPQAYPPQTPPYSYMNNPPPQGPPPQMAPHHPNPYQPPPPAPNYADYYP 645
            |..|.........|.......|...                                       |
  Fly   397 RPTTTTSTTKATQPTKKSTVRPTTR---------------------------------------P 422

  Fly   646 VSGPGLPPQPQPPMTTPPTTTTTTTTPRPHVYSKYVCGVKGTLRTGRSQALSFVSYARAKYGVQR 710
            .||..|.||.:     ||||||||||.
  Fly   423 TSGLVLIPQKK-----PPTTTTTTTTE-------------------------------------- 444

  Fly   711 TARQMTSAAGYSPNFNKSNERLVLGSAIVPIQIHN-DKLGDLVESSSLQSNQLRSYHNHQAQADQ 774
                                        ||::... |::|:
  Fly   445 ----------------------------VPLEPEGLDEIGN------------------------ 457

  Fly   775 PDLVYPEYYQQRSLYGLQSNFSGRRRARVVGGEDGENGEWCWQVALI---NSLNQYLCGAALIGT 836
             ::|.|:.      .|.|...:|    |:|||.:..||:|.|..|:.   ....::.||.:||||
  Fly   458 -NIVDPDE------CGQQEYSTG----RIVGGVEAPNGQWPWMAAIFLHGPKRTEFWCGGSLIGT 511

  Fly   837 QWVLTAAHCVTNIVRSGDA---IYVRVGDYDLTRKYGSPGAQTLRVATTYIHHNHNSQTLDNDIA 898
            :::||||||..:..:...|   ..||:||.||:.........|..|.....|...:.....||||
  Fly   512 KYILTAAHCTRDSRQKPFAARQFTVRLGDIDLSTDAEPSDPVTFAVKEVRTHERFSRIGFYNDIA 576

  Fly   899 LLKLHGQAELRDGVCLVCLPARGV-----SHAAGKRCTVTGYGYMGEAGPIPLRVREAEIPIVSD 958
            :|.|.........|..|||| :|:     ....|:|.||.|:|.....|......|:||:||..:
  Fly   577 ILVLDKPVRKSKYVIPVCLP-KGIRMPPKERLPGRRATVVGWGTTYYGGKESTSQRQAELPIWRN 640

  Fly   959 TECIRKVNAVTEKIFILPASSFCAG-GEEGHDACQGDGGGPLVCQDDGFYELAGLVSWGFGCGRQ 1022
            .:|.|.......:.||      ||| .:.|.||||||.||||:.:.|..:...|:||:|..||..
  Fly   641 EDCDRSYFQPINENFI------CAGYSDGGVDACQGDSGGPLMMRYDSHWVQLGVVSFGNKCGEP 699

  Fly  1023 DVPGVYVKTSSFIGWI 1038
            ..||||.:.:.::.||
  Fly   700 GYPGVYTRVTEYLDWI 715

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mas	NP_523919.1	Tryp_SPc	803..1041	CDD:238113	85/248 (34%)
CG7432	NP_650825.2	CLIP	335..378	CDD:197829	13/52 (25%)
		Tryp_SPc	474..715	CDD:214473	84/247 (34%)
		Tryp_SPc	475..718	CDD:238113	85/248 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010