DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment mas and CG14642

DIOPT Version :9

Sequence 1:	NP_523919.1	Gene:	mas / 38499	FlyBaseID:	FBgn0011653	Length:	1047	Species:	Drosophila melanogaster
Sequence 2:	NP_001246901.1	Gene:	CG14642 / 40532	FlyBaseID:	FBgn0037222	Length:	392	Species:	Drosophila melanogaster

Alignment Length:	529	Identity:	126/529 - (23%)
Similarity:	180/529 - (34%)	Gaps:	177/529 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   537 CIVSLLSFTCFKNAEMTDLFRCKRSGQICCAPKSKILEKQQFQTRNDTAYYPAPPPPPIGPPQAY 601
            |::|.:...|..|.....|           .|:.::...|....|:           |:.....:
  Fly     8 CLISFIGLWCLSNTHTQRL-----------PPEGRMRPLQDDSIRS-----------PVDRDIVF 50

  Fly   602 PPQTPPYSYMNNPPPQGPPPQMAPHHPNPYQ------PPPPAPNYADYYPVSGPGLPPQPQPPMT 660
            |.       ::..|  |.|.:....|...:|      |..|.|....|.|   |.:|.||.||
  Fly    51 PE-------LDAGP--GKPEEKMWFHITDFQFDRVEGPTQPKPKPRQYPP---PPMPGQPFPP-- 101

  Fly   661 TPPTTTTTTTTPRPHVYSKYVCGVKGTLRTGRSQALSFVSYARAKYGVQRTARQMTSAAGYSPNF 725
             ||                                                       .|:....
  Fly   102 -PP-------------------------------------------------------GGFKKKE 110

  Fly   726 NKSNERLVLGSAIVPIQIHNDKLGDLVESSSLQSNQLRSYHNHQA-QADQPDLVYPEYYQQRSLY 789
            ||..            ::...|..:.||         |.:.|..| .||..|
  Fly   111 NKQR------------RLCEQKYSEYVE---------RIFPNDTAVAADAND------------- 141

  Fly   790 GLQSNFSGRRRAR-------VVGGEDGENGEWCWQVALINSLNQYLCGAALIGTQWVLTAAHCVT 847
               ::|.||..||       ...|.:.:.|    ||       .|.||.:||..::|||||||.:
  Fly   142 ---ADFDGRVLARPGEYPHMAAVGFESDRG----QV-------DYKCGGSLISERFVLTAAHCTS 192

  Fly   848 NIVRSGDAIYVRVGDYDLTRKYGSPGAQTLRVATTYIHHNHNSQTLDNDIALLKLHGQAELRDGV 912
              :......:||:||.||..:..|..||.||:...:.|.|:..:...:|||||||..:.||.:.|
  Fly   193 --IYEAPPKWVRIGDLDLASEKRSVEAQLLRIEQVFAHPNYKKKMYYDDIALLKLEKEVELTEYV 255

  Fly   913 CLVCL---PARGVSHAAGKRCTVTGYGYMGEAGPIPLRVREAEIPIVSDTECIRKVNAVTEKIFI 974
            ..|.|   |....:.|     ...|||....|.|:..|:....:.:|.:.||..::..:.|....
  Fly   256 RPVRLWVFPELPTTIA-----FAMGYGATSFAKPMTNRLTNLNLTVVPNAECNAELPPLAETPSG 315

  Fly   975 LPASSFCAGGEE---GHDACQGDGGGPLVCQDDG-------FYELAGLVSWGFGCGRQDVPGVYV 1029
            :..|..||  ::   ..|.||||.||||.....|       .|.|.|:.|:|..| |...|.||.
  Fly   316 VLESQICA--QDYILNRDTCQGDSGGPLQLNLPGRRRGHRIHYHLIGITSYGVFC-RSSYPSVYT 377

  Fly  1030 KTSSFIGWI 1038
            :.|||:.||
  Fly   378 RVSSFLDWI 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
mas	NP_523919.1	Tryp_SPc	803..1041	CDD:238113	81/249 (33%)
CG14642	NP_001246901.1	Tryp_SPc	146..387	CDD:238113	85/262 (32%)
CG14642	NP_001246901.1	Tryp_SPc	146..386	CDD:214473	83/260 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456046
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24258
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940