DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1299 and TMPRSS13

DIOPT Version :9

Sequence 1:NP_647862.1 Gene:CG1299 / 38496 FlyBaseID:FBgn0035501 Length:511 Species:Drosophila melanogaster
Sequence 2:NP_001070731.1 Gene:TMPRSS13 / 84000 HGNCID:29808 Length:567 Species:Homo sapiens


Alignment Length:345 Identity:102/345 - (29%)
Similarity:161/345 - (46%) Gaps:60/345 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   178 KECASLLNELRSRSQDATFANFLRASNAVCQNKGTQVCCPTGQGITNTTPAPSQIVPKNTDEIPR 242
            |.|..|..|...|:.:....:|..:.:.:..|.       |.|...:.:..|||           
Human   261 KTCQQLGFESAHRTTEVAHRDFANSFSILRYNS-------TIQESLHRSECPSQ----------- 307

  Fly   243 RLLNVE-EGCG--STVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAA 304
            |.:::: ..||  :..|   :||||.::....|||...|.:    |:...||||||.|:.|||||
Human   308 RYISLQCSHCGLRAMTG---RIVGGALASDSKWPWQVSLHF----GTTHICGGTLIDAQWVLTAA 365

  Fly   305 HCI---RQDL---QFVRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEF 363
            ||.   |:.:   ..|..|..:|....|..    :||..:.:.:|.......|:|::.|.:.:..
Human   366 HCFFVTREKVLEGWKVYAGTSNLHQLPEAA----SIAEIIINSNYTDEEDDYDIALMRLSKPLTL 426

  Fly   364 TSKIAPICLP---HTANLRQKSYVGYMPFVAGWGKTME-GGESAQVLNELQIPIYDNKVCVQSYA 424
            ::.|.|.|||   .|.:|.:..:      :.|:|||.| ..:::..|.|:|:.:.|.|.|     
Human   427 SAHIHPACLPMHGQTFSLNETCW------ITGFGKTRETDDKTSPFLREVQVNLIDFKKC----- 480

  Fly   425 KEKRYFSADQF-DKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPN 488
              ..|...|.: ...::|||.|.||:|:|||||||||:..:    ..|:||.||.|:|.||.:.|
Human   481 --NDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQ----NNRWYLAGVTSWGTGCGQRN 539

  Fly   489 VPGVYSSTQYFMDWIIQQVQ 508
            .||||:.....:.||..:::
Human   540 KPGVYTKVTEVLPWIYSKME 559

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1299NP_647862.1 CLIP 37..93 CDD:197829
CLIP 164..216 CDD:288855 7/37 (19%)
Tryp_SPc 260..503 CDD:214473 84/253 (33%)
Tryp_SPc 261..503 CDD:238113 84/252 (33%)
TMPRSS13NP_001070731.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..115
13 X 5 AA repeats of A-S-P-A-[GLQR] 9..93
4 X 5 AA repeats of T-P-P-G-R 14..68
DUF3682 16..>87 CDD:289231
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 131..157
SRCR_2 231..320 CDD:292133 15/76 (20%)
Tryp_SPc 325..554 CDD:214473 84/253 (33%)
Tryp_SPc 326..557 CDD:238113 86/255 (34%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X11
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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