DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and cfbl

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001077327.1	Gene:	cfbl / 792472	ZFINID:	ZDB-GENE-030131-2319	Length:	751	Species:	Danio rerio

Alignment Length:	314	Identity:	83/314 - (26%)
Similarity:	137/314 - (43%)	Gaps:	72/314 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   235 KNTDEIPRRLLN-VEEG-----CGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGT 293
            |:.|::.....| ::||     ||....|..:   .|..::..:||:|.:.....:|...||.|:
Zfish   435 KSLDDLKETFDNMIDEGNSVELCGLYKDYDDE---SESHKRRQYPWLAKISVTRSTGKNSKCMGS 496

  Fly   294 LITARHVLTAAHCIRQDLQFVRLGEHD----LSTDTETGHVDINIARYVSHPDYNRRNGRS---- 350
            .:|:..:||||||.:.|         |    ::.|.|:.:..|.:....||||||.:...:
Zfish   497 FVTSSFILTAAHCFKVD---------DTPATITIDLESENQGIKVKYIHSHPDYNIKAKLNLGIP 552

  Fly   351 -----DMAILYLERNVEFTSKIAPICLPHTAN----LRQKSYVG--------YMPFVAGWGKTME 398
                 |:|:|.||:.|:.:..:.|||:|.|..    ||.....|        .|.     |:|::
Zfish   553 EYYEFDVALLQLEKPVKMSVSLRPICIPCTKETNGALRLSDREGTCKKHKELLMT-----GETVK 612

  Fly   399 GGESAQVLNELQ---IPIYDNKV---CVQSYAKEKRYFSADQFDKAV----LCAGVLSGGKD--T 451
            ....::|..:.:   |.|...|:   ||:. ||:....:|::....|    ||:|.:....|  .
Zfish   613 AAFMSEVRTKTEQKDITIKQGKLRQACVED-AKKAAGMTAEKATDIVTDNFLCSGGIDPTTDEIA 676

  Fly   452 CQGDSGG-PLMLPEPYQGQLRFYLIGVVSYGIG--CARPNVPGVYSSTQYFMDW 502
            |:||||| ..::|..     |...:|:||:|:.  |.|...|   .|..|..|:
Zfish   677 CKGDSGGATFVVPGG-----RVVQVGIVSWGVKDLCKRSPKP---RSESYTRDY 722

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	75/283 (27%)
		Tryp_SPc	261..503	CDD:238113	75/282 (27%)
cfbl	NP_001077327.1	CCP	87..142	CDD:214478
		CCP	149..202	CDD:153056
		vWFA	250..445	CDD:294047	2/9 (22%)
		Tryp_SPc	471..720	CDD:214473	73/271 (27%)
		Tryp_SPc	471..720	CDD:238113	73/271 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910