DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Prss8

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_579929.1	Gene:	Prss8 / 76560	MGIID:	1923810	Length:	339	Species:	Mus musculus

Alignment Length:	276	Identity:	93/276 - (33%)
Similarity:	138/276 - (50%)	Gaps:	36/276 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 EEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCI----R 308
            |..||:.:.  .:|.||..::.|.|||...:.||    ....|||:|::.:.|::||||.    .
Mouse    34 EASCGAVIQ--PRITGGGSAKPGQWPWQVSITYD----GNHVCGGSLVSNKWVVSAAHCFPREHS 92

  Fly   309 QDLQFVRLGEHDL---STDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPI 370
            ::...|:||.|.|   |.||    |...:|:.::|..|.....:.|:|::.|...|.|:..|.||
Mouse    93 REAYEVKLGAHQLDSYSNDT----VVHTVAQIITHSSYREEGSQGDIALIRLSSPVTFSRYIRPI 153

  Fly   371 CLPHTANLRQKSYVGYMPFVAGWGKTMEGG--ESAQVLNELQIPIYDNKVC-----VQSYAKEKR 428
            ||| .||....:  |....|.|||......  ::.:.|.:|::|:...:.|     :.:..:|..
Mouse   154 CLP-AANASFPN--GLHCTVTGWGHVAPSVSLQTPRPLQQLEVPLISRETCSCLYNINAVPEEPH 215

  Fly   429 YFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVY 493
            ....|     :||||.:.||||.|||||||||..  |.:|  .:||.|:||:|..|..||.||||
Mouse   216 TIQQD-----MLCAGYVKGGKDACQGDSGGPLSC--PMEG--IWYLAGIVSWGDACGAPNRPGVY 271

  Fly   494 SSTQYFMDWIIQQVQD 509
            :.|..:..||...|.:
Mouse   272 TLTSTYASWIHHHVAE 287

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	87/256 (34%)
		Tryp_SPc	261..503	CDD:238113	87/255 (34%)
Prss8	NP_579929.1	Tryp_SPc	45..284	CDD:238113	89/258 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910