DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Prss32

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_081496.2	Gene:	Prss32 / 69814	MGIID:	1917064	Length:	334	Species:	Mus musculus

Alignment Length:	304	Identity:	91/304 - (29%)
Similarity:	141/304 - (46%)	Gaps:	45/304 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   230 SQIVPKNTDE----IPRRLLNVEEGCG--STVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPF 288
            |:::|.::|.    ..||.::::..||  .|.|   :||.|:.::.|.|||...:    ......
Mouse    20 SEVLPTDSDSPSTTTGRRSIDLDSVCGRPRTSG---RIVSGQDAQLGRWPWQVSV----RENGAH 77

  Fly   289 KCGGTLITARHVLTAAHCIRQ----DLQFVRLGEHDLSTDTETGHVDIN-------IARYVSHPD 342
            .|||:||....|||||||..|    .:..|.||       |.:.:.:.|       :|:::.||.
Mouse    78 VCGGSLIAEDWVLTAAHCFNQGQSLSIYTVLLG-------TISSYPEDNEPKELRAVAQFIKHPS 135

  Fly   343 YNR-RNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPFVAGWGK--TMEGGESAQ 404
            |:. .:...|:|::.|...:.|...:.|:|||...:....   |.|.:|.|||.  |.:......
Mouse   136 YSADEHSSGDIALVQLASPISFNDYMLPVCLPKPGDPLDP---GTMCWVTGWGHIGTNQPLPPPF 197

  Fly   405 VLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQ 469
            .|.|||:|:.|.:.|...|.:.....:.....:.:||||...|.||.|.|||||||:.      .
Mouse   198 TLQELQVPLIDAETCNTYYQENSIPGTEPVILEGMLCAGFQEGKKDACNGDSGGPLVC------D 256

  Fly   470 LRFYLI--GVVSYGIGCARPNVPGVYSSTQYFMDWIIQQVQDTP 511
            :....|  ||||:|..||....||||::...::.||...:.:.|
Mouse   257 INDVWIQAGVVSWGSDCALFKRPGVYTNVSVYISWIQNTMWNLP 300

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	79/258 (31%)
		Tryp_SPc	261..503	CDD:238113	79/257 (31%)
Prss32	NP_081496.2	Tryp_SPc	53..292	CDD:214473	79/258 (31%)
Prss32	NP_081496.2	Tryp_SPc	54..295	CDD:238113	81/260 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.910