DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and Gzmn

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_038949596.1	Gene:	Gzmn / 691668	RGDID:	1597226	Length:	465	Species:	Rattus norvegicus

Alignment Length:	351	Identity:	91/351 - (25%)
Similarity:	165/351 - (47%)	Gaps:	69/351 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   181 ASLLNELRSRSQDATFANFLRASNAVCQ------NKGTQVCCPTGQGITNTTPAPSQ----IVPK 235
            ::||.|          |..:...:|.|:      ::.|::|.    |..|...|||:    ....
  Rat   159 SALLEE----------AELIIQGDAECKKRFRHYSETTEICA----GDPNEIEAPSKGCVCSALL 209

  Fly   236 NTDEIPRR----------LLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKC 290
            :...:|.:          ||.:|.|.       ::|:||...:..::|::|.:......|:...|
  Rat   210 HLSRLPGKMPPVLILLTLLLPLEAGA-------EEIIGGHEVKPHSYPYMAFIQSVKADGNISYC 267

  Fly   291 GGTLITARHVLTAAHCIRQDLQFVRLGEHDLSTDTETGHVDINIARYVSHPDYNRRNGRSDMAIL 355
            ||.|:....|||||||..:.:. |.||.|::....:|..: |::.:.:|||.||:.:...|:.:|
  Rat   268 GGFLVQDYFVLTAAHCEGESMT-VMLGAHNIKAKEDTQQI-ISVEKAISHPAYNKVDYSYDIMLL 330

  Fly   356 YLERNVEFTSKIAPICLPHT-ANLRQKSYVGYMPFVAGWGKT-MEGGESAQVLNELQIPIYDNKV 418
            .|:...:.|..::.:.||.: |.::.    |.:..|||||.| :.|.:.:..|.|.::.|.:::.
  Rat   331 KLKSKAKRTKAVSTLMLPQSDAQVKP----GDVCHVAGWGLTSINGTKVSSCLREAELIIQEDQE 391

  Fly   419 CVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIG 483
            |      ||.::  :.|....:|||..:..:|..:|||||||:...      |.|  ||::||
  Rat   392 C------EKIFY--NYFKTIQICAGDPNNVQDASKGDSGGPLVCDN------RAY--GVIAYG-- 438

  Fly   484 CARPNV-PGVYSSTQYFMDWIIQQVQ 508
             .:..: .||::...||:.||.:.::
  Rat   439 -KKGEISSGVFTKVVYFLPWISRNMK 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	7/40 (18%)
		Tryp_SPc	260..503	CDD:214473	71/245 (29%)
		Tryp_SPc	261..503	CDD:238113	71/244 (29%)
Gzmn	XP_038949596.1	Tryp_SPc	21..>194	CDD:238113	9/48 (19%)
Gzmn	XP_038949596.1	Tryp_SPc	238..461	CDD:238113	73/247 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910