DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and Klk5

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_081082.1	Gene:	Klk5 / 68668	MGIID:	1915918	Length:	293	Species:	Mus musculus

Alignment Length:	307	Identity:	93/307 - (30%)
Similarity:	139/307 - (45%)	Gaps:	56/307 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 PTGQGITNTTPAPSQIVPKNTDEIPRRLLNVEEGCGSTV--GYFKKIVGGEVSRKGAWPW--IAL 277
            |...|..::...||...|..|:    |.|:.:...|...  ....:||.|...:|.|.||  ..|
Mouse    26 PVLAGDVSSCDNPSGTEPSGTN----RDLSTDSKSGEDTRSDSSSRIVNGSDCQKDAQPWQGALL 86

  Fly   278 LGYDDPSGSPFK--CGGTLITARHVLTAAHCIRQDLQFVRLGEHDLSTDTETGHVDINIARYVSH 340
            ||       |.|  ||..||:.:.:|||||| |:.:..:|||.|.:|...|:|.......:.:.|
Mouse    87 LG-------PNKLYCGAVLISPQWLLTAAHC-RKPVFRIRLGHHSMSPVYESGQQMFQGIKSIPH 143

  Fly   341 PDYNRRNGRSDMAILYLERNVEFTSKIAPI-----CLPHTANLRQKSYVGYMPFVAGWGKTMEGG 400
            |.|:.....:|:.::.:.|.:..:..:.|:     |...          |....|:|||.|....
Mouse   144 PGYSHPGHSNDLMLIKMNRKIRDSHSVKPVEIACDCATE----------GTRCMVSGWGTTSSSH 198

  Fly   401 ES-AQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPE 464
            .: .:||..|.|.:...:.|..||        ..|.||.:.|||. ..|:|:||||||||::.
Mouse   199 NNFPKVLQCLNITVLSEERCKNSY--------PGQIDKTMFCAGD-EEGRDSCQGDSGGPVVC-- 252

  Fly   465 PYQGQLRFYLIGVVSYG-IGCARPNVPGVYSSTQYFMDWIIQQVQDT 510
              .|:|:    |:||:| ..||:.|.||||::...|:.||    :||
Mouse   253 --NGKLQ----GLVSWGDFPCAQRNRPGVYTNLCEFVKWI----KDT 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	80/253 (32%)
		Tryp_SPc	261..503	CDD:238113	80/252 (32%)
Klk5	NP_081082.1	Tryp_SPc	67..286	CDD:214473	80/253 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910