DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG1299 and 2210010C04Rik

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_075822.3	Gene:	2210010C04Rik / 67373	MGIID:	1914623	Length:	247	Species:	Mus musculus

Alignment Length:	249	Identity:	89/249 - (35%)
Similarity:	135/249 - (54%)	Gaps:	29/249 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   260 KIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQFVRLGEHDLSTD 324
            |||||...::.|.|:...|.    ||..| |||:||.::.|::||||.:..:| ||||||::..
Mouse    24 KIVGGYTCQRNALPYQVSLN----SGYHF-CGGSLINSQWVVSAAHCYKSRIQ-VRLGEHNIDA- 81

  Fly   325 TETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLPHTANLRQKSYVGYMPF 389
            .|.|...|:.|:.:.||:||.....:|:.::.|:......|:::.:.||     |.....|....
Mouse    82 LEGGEQFIDAAKIIRHPNYNANTYNNDIMLIKLKTAATLNSRVSTVALP-----RSCPSAGTRCL 141

  Fly   390 VAGWGKTMEGGES-AQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQ 453
            |:|||.|:..|.: ..:|..|..|:..:..|..||..:   .:::.|     |.|.|.||||:||
Mouse   142 VSGWGNTLSSGTNYPSLLQCLDAPVLSDSSCTSSYPGK---ITSNMF-----CLGFLEGGKDSCQ 198

  Fly   454 GDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQV 507
            ||||||::.    .|||:    ||||:|.|||:...||||:....:::||.|.:
Mouse   199 GDSGGPVVC----NGQLQ----GVVSWGYGCAQRGKPGVYTKVCKYVNWIQQTI 244

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	86/243 (35%)
		Tryp_SPc	261..503	CDD:238113	85/242 (35%)
2210010C04Rik	NP_075822.3	Tryp_SPc	24..240	CDD:214473	86/243 (35%)
2210010C04Rik	NP_075822.3	Tryp_SPc	25..243	CDD:238113	87/245 (36%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910