DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and CG18754

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_652652.3	Gene:	CG18754 / 59145	FlyBaseID:	FBgn0042106	Length:	341	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	99/366 - (27%)
Similarity:	151/366 - (41%)	Gaps:	94/366 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   170 KPGNCVEIKECASLLNELRSRSQDATFANFLRASNAVCQNKGTQ------VCCPTGQGITNTTPA 228
            |...|..:..|:.|:|.||.|.......:............|.:      |||
  Fly    32 KDEKCTRLVSCSPLMNILRPRGMTQAEKDVFAHRQCGLDPNGHELLHMVYVCC------------ 84

  Fly   229 PSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGT 293
                 |:..|.:|.:     :.||.|...|:. .|.|.:....:||:.||.|::          .
  Fly    85 -----PELGDVLPNK-----QTCGQTTPVFRD-RGAENAELNEYPWMVLLLYEN----------R 128

  Fly   294 LITARHVLTAAHCI------RQD--LQFVRLGEHD---LSTDTETGHVDINIARYVSHPDYNRRN 347
            |...|:|||||||:      :.|  |:.|||||..   :::::...|:|:.:.:...|..:....
  Fly   129 LSLIRYVLTAAHCVIGGYLTQNDLVLKSVRLGESTTDCITSESRCPHLDVEVGQTTVHQGFTSSG 193

  Fly   348 G--RSDMAILYLERNVEFTSKIAPICL-----P-HTANLRQKSYVGYMPFVAGWGKTMEGGESAQ 404
            |  |:|:|:|.|:..|.:|.||.||||     | ...||:          ::||..|    :|:|
  Fly   194 GTYRNDIALLRLQFPVRYTKKIQPICLLDAEFPLQDLNLQ----------ISGWDPT----KSSQ 244

  Fly   405 VLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQ 469
            .|....:...:...|:..|..   :.||.|     :|||....| |||.|.||.|:|      |.
  Fly   245 TLITSTVKERNPADCLNRYPS---FRSASQ-----VCAGGQRKG-DTCAGISGSPVM------GI 294

  Fly   470 LR------FYLIGVVSYGIG-CARPNVPGVYSSTQYFMDWI 503
            :.      .:|.|:.|||.. |....:||||:...:|.:||
  Fly   295 MGSGVDEFVFLAGIASYGQQYCYSAGIPGVYTKIGHFSEWI 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855	10/51 (20%)
		Tryp_SPc	260..503	CDD:214473	78/268 (29%)
		Tryp_SPc	261..503	CDD:238113	78/267 (29%)
CG18754	NP_652652.3	CLIP	35..84	CDD:288855	9/48 (19%)
		Tryp_SPc	108..338	CDD:238113	80/267 (30%)
		Tryp_SPc	108..335	CDD:214473	78/265 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D402896at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.920