DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and cfd

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001018368.1	Gene:	cfd / 553553	ZFINID:	ZDB-GENE-050522-411	Length:	249	Species:	Danio rerio

Alignment Length:	252	Identity:	77/252 - (30%)
Similarity:	126/252 - (50%)	Gaps:	38/252 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   261 IVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQDLQF----VRLGEHDL 321
            |.||:.::..:.|::|.:.::    ...:|||.||:::.|::||||. ||.:.    |.||.|.|
Zfish    21 ITGGQEAKAHSRPYMASVQWN----GKHECGGFLISSQWVMSAAHCF-QDGRTSGVKVVLGAHSL 80

  Fly   322 STDTETGHV-DINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICL--PHTANLRQKSY 383
            |...:|... |   |...:|||::..|..:|:|::.|::.|..:..:.|:..  ..||:.::.:.
Zfish    81 SGAEDTKQTFD---AEVYNHPDFSISNYDNDIALIKLDKPVTQSDAVKPVKFQRDETADPKEAAV 142

  Fly   384 VGYMPFVAGWGKTMEGGESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFDKAVLCAGVLSGG 448
            |.    .||||.....|.....|:||.||:.:...|      .:..|..::|...:|||.  ...
Zfish   143 VE----TAGWGSLNNMGGRPDKLHELSIPVMERWRC------GRADFYGEKFTSNMLCAA--DKR 195

  Fly   449 KDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIG--CARPNVPGVYSSTQYFMDWI 503
            ||||.|||||||:    |:|    .::|:.|.| |  |.....||:|:...::..||
Zfish   196 KDTCDGDSGGPLL----YRG----IVVGITSNG-GKKCGSSRKPGLYTIISHYASWI 243

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	75/250 (30%)
		Tryp_SPc	261..503	CDD:238113	75/250 (30%)
cfd	NP_001018368.1	Tryp_SPc	21..246	CDD:238113	77/252 (31%)
cfd	NP_001018368.1	Tryp_SPc	21..243	CDD:214473	75/250 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910