DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and ctrb.3

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	NP_001017724.1	Gene:	ctrb.3 / 550419	ZFINID:	ZDB-GENE-050417-229	Length:	265	Species:	Danio rerio

Alignment Length:	264	Identity:	80/264 - (30%)
Similarity:	131/264 - (49%)	Gaps:	29/264 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly   250 GCG-----STVGYFKKIVGGEVSRKGAWPWIALLGYDDPSGSPFKCGGTLITARHVLTAAHCIRQ 309
            |||     ..|..:.:||.||.:...:|||...|  .|.:|..| |||:||....|:|||||..:
Zfish    18 GCGVPAIPPVVSGYARIVNGEEAVPHSWPWQVSL--QDFTGFHF-CGGSLINEFWVVTAAHCSVR 79

  Fly   310 DLQFVRLGEHDL-STDTETGHVDINIARYVSHPDYNRRNGRSDMAILYLERNVEFTSKIAPICLP 373
            ....|.||||:. .::|:.....:.:::..:||.||.....:|:|::.|.......:.::|:||.
Zfish    80 TSHRVILGEHNKGKSNTQEDIQTMKVSKVFTHPQYNSNTIENDIALVKLTAPASLNAHVSPVCLA 144

  Fly   374 HTANLRQKSYVGYMPFV-AGWGKTMEGG-ESAQVLNELQIPIYDNKVCVQSYAKEKRYFSADQFD 436
            ..::    ::...|..| :|||.|.... .:...|.::.:|:..|:.|       |.::.::..|
Zfish   145 EASD----NFASGMTCVTSGWGVTRYNALFTPDELQQVALPLLSNEDC-------KNHWGSNIRD 198

  Fly   437 KAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQGQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMD 501
             .::|||  :.|..:|.|||||||:.    |....:.|:|:||:|.....|.:||||.......|
Zfish   199 -TMICAG--AAGASSCMGDSGGPLVC----QKDNIWTLVGIVSWGSSRCDPTMPGVYGRVTELRD 256

  Fly   502 WIIQ 505
            |:.|
Zfish   257 WVDQ 260

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	74/245 (30%)
		Tryp_SPc	261..503	CDD:238113	74/244 (30%)
ctrb.3	NP_001017724.1	Tryp_SPc	33..258	CDD:214473	74/245 (30%)
ctrb.3	NP_001017724.1	Tryp_SPc	34..261	CDD:238113	76/248 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910