DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1299 and prss27

DIOPT Version :9

Sequence 1:	NP_647862.1	Gene:	CG1299 / 38496	FlyBaseID:	FBgn0035501	Length:	511	Species:	Drosophila melanogaster
Sequence 2:	XP_031749235.1	Gene:	prss27 / 496619	XenbaseID:	XB-GENE-5744470	Length:	724	Species:	Xenopus tropicalis

Alignment Length:	302	Identity:	97/302 - (32%)
Similarity:	144/302 - (47%)	Gaps:	36/302 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   217 PTGQGITNTTPAPSQIVPKNTDEIPRRLLNVEEGCGSTVGYFKKIVGGEVSRKGAWPWIALLGYD 281
            |..|.:...||....|.|..||            ||..: ...:|:||:.:::|.|||  .:.:.
Frog     3 PLLQALLLLTPGLLGITPGATD------------CGIPL-VSSRIMGGQSAQEGQWPW--QVSFR 52

  Fly   282 DPSGSPFKCGGTLITARHVLTAAHCIRQDLQ----FVRLGEHDLSTDTETGH-VDINIARYVSHP 341
            : :|..| ||||||:.::|::||||......    ...||.:.:  |...|: |.|.:....::|
Frog    53 N-NGGHF-CGGTLISKQYVISAAHCFPSSSSASSVTAVLGAYMI--DQPDGNQVAIPVQSATNYP 113

  Fly   342 DYNRRNGRSDMAILYLERNVEFTSKIAPICLP-HTANLRQKSYVGYMPFVAGWGKTMEGGE--SA 403
            .|.......|::::.|...|.||:.|.|:||| .|....    .|...:|.|||.......  |.
Frog   114 SYVNEGDSGDISLVQLASPVTFTNYILPVCLPADTVTFP----TGLQCWVTGWGNIASDVSLVSP 174

  Fly   404 QVLNELQIPIYDNKVCVQSYAKEKRY-FSADQFDKAVLCAGVLSGGKDTCQGDSGGPLMLPEPYQ 467
            ..|.|:.:|:.|...|...|.....| .|:......::|||.::||||:|||||||||:...  .
Frog   175 MTLQEVAVPLIDANECNALYQTPNSYGTSSISVHSDMICAGFINGGKDSCQGDSGGPLVCSS--S 237

  Fly   468 GQLRFYLIGVVSYGIGCARPNVPGVYSSTQYFMDWIIQQVQD 509
            ||  ::|.||||:|.||.:...||||:....:.|||:....|
Frog   238 GQ--WFLAGVVSFGEGCGQAYRPGVYTLMPSYTDWIVSYASD 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1299	NP_647862.1	CLIP	37..93	CDD:197829
		CLIP	164..216	CDD:288855
		Tryp_SPc	260..503	CDD:214473	84/251 (33%)
		Tryp_SPc	261..503	CDD:238113	84/250 (34%)
prss27	XP_031749235.1	Tryp_SPc	34..271	CDD:238113	84/250 (34%)
prss27	XP_031749235.1	Tryp_SPc	420..659	CDD:238113
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910